Composition
Composition per tablet:
Hydrolysis lignin ( in terms of dry matter) – 355 mg
Lactulose (in terms of 100% substance) – 120 mg
Auxiliary substances:
Croscarmellose sodium – 20 mg
Magnesium stearate-5 mg
Microcrystalline cellulose-to obtain a tablet weighing 550 mg
Pharmacological action
The pharmacological action of the drug is due to the properties of the active components included in the composition – lignin and lactulose.
Hydrolysis lignin – a natural enterosorbent consisting of hydrolysis products of wood components, has a high sorbing activity and a non-specific detoxification effect.
Binds in the intestines and removes from the body pathogenic bacteria and bacterial toxins, drugs, heavy metal salts, alcohol, allergens, as well as an excess of certain metabolic products, including bilirubin, cholesterol, histamine, serotonin, urea, and other metabolites responsible for the development of endogenous toxicosis. Non-toxic, non-absorbed, completely eliminated from the intestine within 24 hours.
Lactulose is a synthetic disaccharide whose molecule consists of galactose and fructose residues. Lactulose in the stomach and upper intestines is not absorbed or hydrolyzed. Lactulose released from tablets in the large intestine as a substrate is fermented by the normal intestinal microflora, stimulating the growth of bifidobacteria and lactobacilli.
As a result of the hydrolysis of lactulose in the large intestine, organic acids are formed – lactic, acetic and formic, which inhibit the growth of pathogenic microorganisms and, as a result, reduce the production of nitrogen-containing toxic substances.
The described process leads to an increase in osmotic pressure in the lumen of the large intestine and stimulation of peristalsis. The complex action of the drug is aimed at normalizing the microbiocenosis of the large intestine and reducing the intensity of endogenous toxic conditions.
The use of the drug in the complex therapy of bacterial vaginosis (vaginal dysbiosis) leads to an increase in the effectiveness of therapy, including an increase in the number of lactobacilli in the vagina, as well as effective suppression of the growth of conditionally pathogenic flora.
Indications
Disorders of the intestinal microflora (intestinal dysbiosis), including as a result of antibiotic therapy; in the complex therapy of irritable bowel syndrome, hepatitis and cirrhosis of the liver; allergic diseases (atopic dermatitis, urticaria), bacterial vaginosis (vaginal dysbiosis).
Use during pregnancy and lactation
There are no data on the safety of using the drug Lactofiltrum during pregnancy, lactation and in children.
Contraindications
Individual intolerance to the drug, intestinal obstruction, gastrointestinal bleeding, galactosemia. It is undesirable to use the drug in case of exacerbation of gastric ulcer and duodenal ulcer, intestinal atony.
Side effects
Possible allergic reactions to the components of the drug, rarely-flatulence, diarrhea.
Interaction
It is possible to reduce the therapeutic effect of some medications taken simultaneously by mouth.
How to take, course of use and dosage
Inside, if necessary, after preliminary grinding, with water, an hour before meals and taking other medications.
In the intestinal dysbiosis:
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adults and children over 12 years: 2-3 tablets 3 times a day; – children from 8 to 12 years: 1-2 tablets 3 times a day;
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children from 3 to 7 years – 1 tablet 3 times a day;
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children from 1 to 3 years – 1/2 tablet 3 times a day.
Bacterial vaginosis (vaginal dysbiosis):
Take 2 tablets 3 times a day.
The average duration of treatment is 2-3 weeks.
Long-term use of the drug and repeated courses of treatment should be carried out only on the recommendation of a doctor.
Overdose
Symptoms: constipation, abdominal pain.
Treatment: discontinuation of the drug.
Special instructions
Precautions when taking the drug
The drug can be used in complex therapy together with other medications, subject to the rule of separate use.
Interaction with alcohol
There are no data on interaction with alcohol.
Conditions of release from pharmacies
The drug is approved for use as an over-the-counter product.
Form of production
Tablets
Storage conditions
In a place protected from moisture and light at a temperature not exceeding 30°C. Keep out of reach of children.
Shelf life
3 years
Active ingredient
Lactulose, Hydrolyzed Lignin
Dosage form
Tablets
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