Lincomycin-ACOS ointment 2%, 15g

Composition

Active ingredient:

lincomycin (in the form of monohydrate hydrochloride) 20 mg

Pharmacological action

Lincomycin ointment – antibacterial. Inhibits bacterial protein synthesis due to reversible binding to the 50S subunit of ribosomes, disrupts the formation of peptide bonds. After oral use,20-30% of the dose is absorbed, the maximum concentration in the blood is reached in 2-4 hours.

Penetrates into bile, bone tissue. It passes poorly through the blood-brain barrier. It is metabolized in the liver. It is excreted in the urine and faeces.

It is effective against gram-positive microorganisms (staphylococci, streptococci, pneumococci, diphtheria bacillus), some anaerobic spore-forming bacteria (Clostridium) and gram-negative anaerobes (bacteroids, mycoplasma).

It acts on microorganisms (especially staphylococci) that are resistant to other antibiotics. Resistance develops slowly. In therapeutic doses, it causes bacteriostasis, in higher doses – cell death.

Indications

Severe infectious and inflammatory diseases: sepsis, acute and chronic osteomyelitis, septic endocarditis, pneumonia, lung abscess, pleural empyema, purulent skin and soft tissue infections, erysipelas, otitis media and other infections caused by microorganisms resistant to penicillins and other antibiotics.

Contraindications

Hypersensitivity, severe liver and/or kidney dysfunction, pregnancy, lactation, early infancy (up to 1 month).

Restrictions for use: fungal diseases of the skin, oral mucosa, vagina, myasthenia gravis (parenteral use).

Side effects

Allergic reactions:  urticaria, exfoliative dermatitis, angioedema, anaphylactic shock.

How to take, course of use and dosage

Lincomycin ointment is applied topically. Apply a thin layer on the affected areas of the skin.

Form of production

ointment for external use

Storage conditions

Store in a dry place, protected from light, at a temperature not exceeding 15 °C.

Shelf life

3 years

Active ingredient

Lincomycin

Conditions of release from pharmacies

By prescription

Dosage form

ointment

Description

Children as prescribed by a doctor, Adults as prescribed by a doctor, Children over 1 month of age

Indications

Purulent Wounds, Skin Infections, Pyoderma, Boils