Loperamide Stada capsules 2mg, 20pcs

Composition

Capsules.

1 capsule contains:

Active ingredient:  

Loperamide hydrochloride 2 mg;

Auxiliary substances:  

Corn starch;

Milk sugar;

Talcum powder.

Aerosil;

Magnesium stearate.

Pharmacological action

Pharmaceutical group:

antidiarrheal agent.

Pharmaceuticaleffect:

 Loperamide binds to opioid receptors of the intestinal wall (stimulation of choline and adrenergic neurons via guanine nucleotides), reduces the tone and motility of intestinal smooth muscles (by inhibiting the release of acetylcholine and PG).

Slows down peristalsis and increases the passage time of intestinal contents. Increases the tone of the anal sphincter, helps to retain fecal matter and reduce the urge to defecate. The action develops quickly and lasts 4-6 hours.

Active ingredients

Loperamide

Indications

Diarrhea (acute and chronic of various origins: allergic, emotional, medicinal, radiation; with changes in the diet and quality of food, with impaired metabolism and absorption).

Regulation of stool in patients with ileostoma.

As an auxiliary drug – diarrhea of infectious origin.

Contraindications

• Hypersensitivity to the drug, lactose intolerance, lactase deficiency or glucose-galactose malabsorption;
• diverticulosis, intestinal obstruction, ulcerative colitis in the acute stage;
• diarrhea on the background of acute pseudomembranous enterocolitis, as monotherapy dysentery and other infections of the gastrointestinal tract;
• pregnancy (I trimester), lactation;
• loperamide capsules are not indicated for children under 6 years.

With caution: liver failure.

Side effects

Allergic reactions (skin rash), drowsiness, dizziness, hypovolemia, electrolyte disturbances;

dryness of the oral mucosa, intestinal colic, gastralgia, abdominal pain or discomfort, nausea, vomiting, constipation, flatulence.

Rarely-urinary retention, extremely rarely-intestinal obstruction.

When taking tablets for resorption – a burning or tingling sensation on the tongue.

Interaction

Opioid analgesics increase the risk of developing severe constipation.

How to take, course of use and dosage

Inside (capsules-without chewing, washed down with water; lingual tablet – on the tongue, within a few seconds it breaks up, after which it is swallowed with saliva, not washed down with water).

In acute diarrhea, adults are prescribed an initial dose of 4 mg; then-2 mg after each act of defecation (in the case of liquid feces); the highest daily dose is 16 mg.

When prescribed in drops: the initial dose is 60 drops of 0.002% solution; then 30 drops after each act of defecation; the maximum dose is 180 drops/day (for 6 times).

With chronic diarrhea, adults are prescribed 4 mg/day. The maximum daily dose is 16 mg.

In acute diarrhea, children over 5 years of age are prescribed an initial dose of 2 mg, then 2 mg after each act of defecation; the maximum daily dose is 8 mg.

Drops: the initial dose is 30 drops of 0.002% solution; then 30 drops 3 times a day; the maximum dose is 120 drops/day (in 4 doses).

With chronic diarrhea, children over 5 years of age are prescribed loperamide in a daily dose of 30 caps or 2 mg.

Children aged 2-5 years are prescribed in an oral solution of 5 ml (1 measuring cap) per 10 kg; the frequency of use is 2-3 times a day.

The maximum daily dose is 6 mg per 20 kg. If there is a normal stool or if there is no stool for more than 12 hours, the drug is canceled.

Overdose

Symptoms:

central nervous system depression (stupor, impaired coordination of movements, drowsiness, miosis, muscle hypertension, respiratory depression), intestinal obstruction.

Treatment:

the antidote is naloxone; given that the duration of action of loperamide is longer than that of naloxone, repeated use of the latter is possible. Symptomatic treatment, activated charcoal, gastric lavage, mechanical ventilation.

Description

Antidiarrheal drugs

Special instructions

If there is no effect after 2 days of using Loperamide, you should consult a doctor.

If constipation or bloating develops during treatment, loperamide should be discontinued. In patients with impaired liver function, careful monitoring for signs of toxic damage to the central nervous system is necessary.

During the treatment of diarrhea, it is necessary to replenish the loss of fluid and electrolytes.

During the treatment period, care should be taken when driving vehicles and doing other activities. potentially dangerous activities that require increased concentration of attention and speed of psychomotor reactions.

Storage conditions

Store in a dry place, protected from light, at a temperature not exceeding 25 °C.

Shelf

life is 2 years.

Active ingredient

Loperamide

Dosage form

Capsules

Description

Pregnant women in the second and third trimester as prescribed by a doctor, Children over 6 years of age, For adults

Indications

Diarrhea