Composition
>of 15 ml of suspension contains: Active ingredients: magnesium hydroxide (as a gel)600 mg; aluminum hydroxide (as a gel)525 mg; Excipients: mannitol – 37.5 mg, citric acid monohydrate – 9.83 mg, hydrochloric acid, concentrated – 21.3 mg, oil of peppermint leaves – 1.89 mg, methyl parahydroxybenzoate – 15 mg, sodium saccharin – 4.21 mg, sorbitol 70% – 214.29 mg, hydrogen peroxide 30% – 9.75 mg, parahydroxybenzoate – 7.5 mg, purified water – 4746.59 mg.
Pharmacological action
Pharm group:
antacid.
Pharmaceutical action: Â
Aluminum hydroxide and magnesium hydroxide neutralize the free hydrochloric acid of gastric juice without causing its secondary hypersecretion. In addition, an increase in the pH of gastric juice when taking Maalox® leads to a decrease in pepsin activity in gastric juice.
The drug also has an adsorbing and enveloping effect, which reduces the impact of damaging factors on the mucous membrane of the esophagus and stomach.
Pharmacokinetics:
Magnesium hydroxide and aluminum hydroxide are considered topical antacids. Due to their low absorption, they do not have a systemic effect.
Indications
- acute gastroduodenitis;
- ulcer disease of stomach and duodenum in the acute phase;
- chronic gastroduodenitis with normal and high secretory function in the acute phase;
- hernia hiatal;
- reflux esophagitis;
- phenomena of dyspepsia (and their prevention) arising out of the use of certain drugs (including NSAIDs, corticosteroids);
- discomfort or pain in the epigastrium, heartburn when errors in diet, excessive consumption of coffee, alcohol, nicotine.
Use during pregnancy and lactation
Contraindicated during pregnancy and lactation.
Contraindications
hypophosphatemia; severe renal failure;fructose intolerance (due to the presence of sorbitol in the drug); hypersensitivity to active substances and other components of the drug; children and adolescents under 15 years of age.
Side effects
Metabolic and nutritional disorders: unknown frequency-hypermagnesemia, hyperaluminemia, hypophosphatemia (with long-term treatment or taking high doses, or with taking standard doses with low phosphate content in food), which can lead to increased bone resorption, hypercalciuria, osteomalacia. Immune system disorders: unknown frequency-hypersensitivity reactions such as pruritus, urticaria, angioedema and anaphylactic reactions. Gastrointestinal disorders: infrequently — diarrhea, constipation.
Interaction
When used concomitantly, Maalox may increase the level of quinidine in the blood plasma, which increases the risk of overdose. When taken concomitantly with Maalox, the absorption of tetracycline antibiotics, phenytoin, ofloxacin, digoxin, ciprofloxacin, Indometacin, acetylsalicylic acid (and other salicylates), beta-blockers, aminazine, diflunisalum, isoniazid, histamine H2-receptor blockers, and phosphorus-containing drugs decreases.
How to take, course of use and dosage
Take orally. Children over 15 years of age and adults. Contents of 1-2 bags (15-30 ml) 1-1.5 hours after eating or if heartburn occurs. Before opening the mini-bag, you should carefully mix its contents, carefully kneading the bag between your fingers. Squeeze the contents of the bag into a spoon or into your mouth (take the suspension without first diluting it). If necessary, you can take an additional dose of the drug 2 hours after the previous dose. The maximum daily dose is 12 packs (180 ml). The course of treatment should not exceed 2-3 months. With occasional use (for example, with discomfort after errors in the diet), take 1-2 packages (15-30 ml) once. For mild renal insufficiency, the maximum daily dose is 8 packages (120 ml), for moderate renal insufficiency, the maximum daily dose is 6 packages (90 ml).
Overdose
Symptoms of an acute overdose with a combination of magnesium and aluminum hydroxide salts include diarrhea, abdominal pain, and vomiting. In patients at risk, taking high doses of the drug may cause or worsen intestinal obstruction or intestinal obstruction. Treatment: Magnesium and aluminum are excreted in the urine. Treatment of acute overdose is carried out by replenishing the loss of forced diuresis and fluid. Patients with renal insufficiency should be treated with hemodialysis or peritoneal dialysis.
Special instructions
When prescribing the drug to children, the dosage regimen is set individually; it is not recommended to use the drug in children under 12 years of age without consulting a doctor. A 2-hour interval should be observed between taking Maalox and other medications.
Form of production
Oral suspension
Storage conditions
Keep out of reach of children at a temperature not exceeding 25°C.
Shelf life
3 years
Active ingredient
Algeldrate, Magnesium Hydroxide
Dosage form
suspension for oral use
Description
Nursing mothers as prescribed by a doctor, For adults, For pregnant women, Children over 15 years of age
Indications
Reflux esophagitis, Flatulence, Diarrhea, Gastric and duodenal ulcers, Gastroduodenitis, Heartburn, Gastritis
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Side effects of Maalox suspension 15ml sachets, 30pcs.
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