Maalox, suspension 250ml

Composition

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of 15 ml of suspension contains:

Active ingredients:  

aluminum hydroxide (as a gel) 525 mg;

magnesium hydroxide (as a gel) 600 mg;

Auxiliary substances:

hydrochloric acid, concentrated – 21.3 mg,

citric acid monohydrate – 9.83 mg

oil peppermint leaves – 1.89 mg,

mannitol – 37.5 mg,

methyl parahydroxybenzoate – 15 mg

parahydroxybenzoate – 7.5 mg,

sodium saccharin – 4.21 mg,

sorbitol 70% – 214.29 mg,

hydrogen peroxide 30% – 9.75 mg,

purified water – 4746.59 mg.

Pharmacological action

Pharm group:

antacid.

Pharmaceutical effect:

Aluminum hydroxide and magnesium hydroxide neutralize the free hydrochloric acid of gastric juice without causing its secondary hypersecretion. In addition, an increase in the pH of gastric juice when taking Maalox® leads to a decrease in pepsin activity in gastric juice.

The drug also has an adsorbing and enveloping effect, which reduces the impact of damaging factors on the mucous membrane of the esophagus and stomach.

Pharmacokinetics:

Magnesium hydroxide and aluminum hydroxide are considered topical antacids. Due to their low absorption, they do not have a systemic effect.

Indications

• Ulcers disease stomach and duodenal ulcers in phase of exacerbation;
• chronic gastroduodenitis with normal and high secretory function in the acute phase;
• acute gastroduodenitis;
• hernia hiatal;
• reflux esophagitis;
• phenomena of dyspepsia (and their prevention) arising out of the use of certain drugs (including NSAIDs, corticosteroids);
• discomfort or pain in the epigastrium, heartburn when errors in diet, excessive consumption of coffee, alcohol, nicotine.

Use during pregnancy and lactation

Contraindicated during pregnancy and lactation.

Contraindications

• Severe renal insufficiency;
• hypersensitivity to active substances and other components of the drug;
• hypophosphatemia;
• fructose intolerance (due to the presence of sorbitol in the drug);
• children and adolescents under 12 years of age.

Side effects

Immune system disorders:  unknown frequency-hypersensitivity reactions such as pruritus, urticaria, angioedema and anaphylactic reactions.

Gastrointestinal disorders:  infrequently — diarrhea, constipation.

Metabolic and nutritional disorders:  unknown frequency-hypermagnesemia, hyperaluminemia, hypophosphatemia (with long-term treatment or taking high doses, or when taking standard doses with low phosphate content in food), which can lead to increased bone resorption, hypercalciuria, osteomalacia.

Interaction

When taken concomitantly with Maalox, the absorption of tetracycline antibiotics, ciprofloxacin, ofloxacin, digoxin, Indometacin, acetylsalicylic acid (and other salicylates), histamine H2-receptor blockers, beta-blockers, aminazine, diflunisalum, isoniazid, phenytoin, and phosphorus-containing drugs decreases. When used simultaneously, Maalox may increase the level of quinidine in the blood plasma, which increases the risk of overdose.

How to take, course of use and dosage

Inside.

Adults and children over 15 years of age. Contents of 1-2 bags (15-30 ml) 1-1.5 hours after eating or if heartburn occurs. Before opening the mini-bag, you should carefully mix its contents, carefully kneading the bag between your fingers. Squeeze the contents of the bag into a spoon or into your mouth (take the suspension without first diluting it).

If necessary, you can take an additional dose of the drug 2 hours after the previous dose. The maximum daily dose is 12 packs (180 ml).

The course of treatment should not exceed 2-3 months. With occasional use (for example, with discomfort after errors in the diet), take 1-2 packages (15-30 ml) once.

For mild renal insufficiency, the maximum daily dose is 8 packages (120 ml), for moderate renal insufficiency, the maximum daily dose is 6 packages (90 ml).

Overdose

Symptoms of an acute overdose with a combination of aluminum hydroxide and magnesium salts include diarrhea, abdominal pain, and vomiting.

In patients at risk, taking high doses of the drug may cause or worsen intestinal obstruction or intestinal obstruction.

Treatment:  aluminum and magnesium are excreted in the urine. Treatment of acute overdose is carried out by replacing fluid loss and forced diuresis. Patients with renal insufficiency should be treated with hemodialysis or peritoneal dialysis.

Special instructions

A 2-hour interval should be observed between taking Maalox and other medications.

When prescribing the drug to children, the dosage regimen is set individually; it is not recommended to use the drug in children under 12 years of age without consulting a doctor.

Form of production

Oral suspension

Storage conditions

At a temperature not exceeding 25°C.

Shelf life

3 years

Active ingredient

Algeldrate, Magnesium Hydroxide

Dosage form

suspension for oral use

Description

Children over 15 years of age, For adults, Nursing mothers as prescribed by a doctor, For pregnant women

Indications

Gastric and Duodenal Ulcers, Flatulence, Heartburn, Diarrhea, Gastroduodenitis, Gastritis, Reflux Esophagitis