Composition
Active ingredient:
melatonin 3 mg;
Auxiliary substances:
calcium phosphate di-substituted;
MCC;
magnesium stearate;
talc;
pharmaceutical glaze;
isopropyl alcohol
Pharmacological action
Melaxen-normalizing biological rhythms, sedative, normalizing physiological sleep, adaptogenic.
Regulates the sleep-wake cycle, daily changes in locomotor activity and body temperature.
Pharmacodynamics
Normalizes circadian rhythms. Accelerates falling asleep, reduces the number of nighttime awakenings, improves well-being after waking up in the morning (does not cause feelings of lethargy, weakness and fatigue when waking up). Adapts the body to the rapid change of time zones, reduces stress reactions.
It has immunostimulating and pronounced antioxidant properties. Inhibits the secretion of gonadotropins, to a lesser extent-other pituitary hormones (corticotropin, thyrotropin, somatotropin). It is not addictive or addictive.
Pharmacokinetics
When taken orally, it is quickly and completely adsorbed, easily passes histohematic barriers, including the BBB. It has a short T1 / 2.
Indications
Sleep disorders, normalization of biological rhythms.
Contraindications
Hypersensitivity, severe renal dysfunction, leukemia, lymphoma, lymphogranulomatosis, myeloma, diabetes mellitus, chronic renal failure.
Side effects
When used in physiological doses, side effects are rare.
While taking melatonin, allergic reactions, edema (in the first week of taking it), headache, nausea, vomiting, diarrhea, and morning drowsiness are described.
Interaction
Increases the effect of drugs that depress the central nervous system, and beta-blockers.
It is not recommended to take together with hormonal drugs, it is incompatible with MAO inhibitors.
How to take, course of use and dosage
Inside,30 to 40 minutes before bedtime.
Adults: 0.5-1 tablet 1 time a day.
As an adaptogen when changing time zones-1 day before the flight and in the next 2-5 days — 1 tablet per day.
The maximum daily dose is up to 2 tablets per day.
Overdose
Symptoms: Â in case of accidental overdose-increased severity of side effects.
Treatment: Â gastric lavage, symptomatic therapy.
Composition
Tablet Form of production
Storage conditions
Store in a dry place, protected from light, at a temperature of 10-30 °C
Shelf life
4 years
Active ingredient
Melatonin
Dosage form
Tablets
Description
For adults
Indications
Weather Sensitivity, Insomnia, Jet Lag, Depression
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Side effects of Melaxen, pills 3mg, 24pcs.
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