Product description
dietary supplements. It is not a medicinal product
Composition
Milk thistle meal “Biocor”,
maltodextrin,
dry oat grass extract,
sugar,
calcium stearic acid,
silicon dioxide.
Pharmacological action
Milk thistle interacts with free radicals in the liver and reduces their toxicity.
Interrupting the process of lipid peroxidation, it prevents further destruction of cellular structures.
In damaged hepatocytes, it stimulates the synthesis of structural and functional proteins and phospholipids (due to specific stimulation of RNA polymerase A), stabilizes cell membranes, prevents the loss of cellular components and intracellular enzymes (transaminases), and accelerates the regeneration of liver cells. Inhibits the penetration of certain hepatotoxic substances (poisons of the pale toadstool fungus) into the cells.
Undergoes enterohepatic circulation. It is metabolized in the liver by conjugation. It is mainly excreted in the bile in the form of glucuronides and sulfates, to a small extent in the urine.
It doesn’t accumulate. After repeated oral use of 140 mg 3 times a day, a stable concentration is achieved.
Improves the general condition of patients with liver diseases, reduces subjective complaints, normalizes laboratory parameters (transaminase activity, gamma-glutamyltransferase, alkaline phosphatase, bilirubin level).
Long-term use significantly increases the survival rate of patients suffering from cirrhosis of the liver.
Indications
- toxic liver damage (alcoholism, intoxication with halogen-containing hydrocarbons, heavy metal compounds, medicinal liver damage) and their prevention;Â
- chronic hepatitis;
- cirrhosis of the liver (as part of complex therapy);
- conditions after infectious and toxic hepatitis; dystrophy and fatty liver infiltration;
- correction of lipid metabolism disorders.
Contraindications
Hypersensitivity
Side effects
- diarrhea;
- allergic reactions;
- children under 12 years of age;
- hypersensitivity to the components of the drug.
Interaction
When Milk Thistle is used together with oral hormonal contraceptives and drugs intended for hormone replacement therapy, it is possible to reduce the effects of the latter.
Silymarin may enhance the effects of diazepam, alprazolam, ketoconazole, lovastatin, and vinblastine due to its inhibitory effect on microsomal cytochrome P 450 enzymes.
How to take, course of use and dosage
Adults and children over 12 years of age: 0.5 teaspoons 2 times a day with meals. The course of admission is 30 days.
Storage conditions
Store in a dry place protected from light at a temperature not exceeding +25°C.
Shelf life
2 years
Conditions of release from pharmacies
Without a prescription
Dosage form
Tablets
Description
Adult
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Side effects of Milk thistle pills Biocor, 60pcs.
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