Nasivin Sensitive, nasal spray 22.5mcg/dose 10ml

Composition

>

1 ml of the solution contains:  

Active ingredient:

Oxymetazoline hydrochloride 0.500 mg;

Auxiliary substances:

citric acid monohydrate 0.609 mg;

sodium citrate dihydrate 3,823 mg;

glycerol (85%) 24,921 mg;

purified water 978,397 mg.

Total: 1008.00 mg, equivalent to 1 ml

Pharmacological action

Nasivin® Sensitive (oxymetazoline) has a vasoconstrictive effect. When applied topically to the inflamed nasal mucosa, it reduces its puffiness and nasal discharge. Restores nasal breathing. Elimination of edema of the nasal mucosa helps restore aeration of the paranasal sinuses of the nasal cavity, the middle ear cavity, which reduces the likelihood of bacterial complications (sinusitis, sinusitis, otitis media). When applied topically intranasally in therapeutic concentrations, it does not irritate or cause hyperemia of the nasal mucosa. Oxymetazoline begins to act quickly, within a few minutes. Duration of action of Nasivin® Sensitive for up to 12 hours. Pharmacokinetics. When applied topically intranasally, oxymetazoline does not have a systemic effect. The half-life of oxymetazoline when administered intranasally is 35 hours. 2.1% of oxymetazoline is excreted in the urine and about 1.1% in the faeces.

Indications

• Acute respiratory diseases with rhinitis symptoms;
• Acute allergic rhinitis;
• Exacerbation of vasomotor rhinitis;
• To facilitate the outflow of discharge from the paranasal sinuses in sinusitis, eustachiitis, otitis media;
• To eliminate edema before diagnostic manipulations in the nasal passages.

Use during pregnancy and lactation

When used during pregnancy or lactation, do not exceed the recommended dose.

The drug can only be used if the potential benefit to the mother exceeds the potential risk to the fetus and child.

Contraindications

• Atrophic rhinitis;
• Angle-closure glaucoma;
• Hypersensitivity to the components of the drug.

Nasivin® Sensitive nasal spray dosed (22.5 mcg / dose) is contraindicated in children under 6 years of age. Use caution when using:

• increased intraocular pressure;
• chronic heart failure;
• arterial hypertension, angina pectoris;
• arrhythmia;
• chronic renal failure;
• in patients with prostatic hyperplasia with clinical symptoms (urinary retention);
• severe atherosclerosis;
• hyperthyroidism;
• diabetes mellitus;
• pheochromocytoma.

Side effects

Infrequently: burning or dryness of the nasal mucosa, sneezing, nosebleeds, angioedema, itching. In rare cases: after the effect of using the drug Nasivin®has passed Sensitive, feeling of” stuffy ” nose (reactive hyperemia). Rare: increased blood pressure, headache, dizziness, palpitation, tachycardia, anxiety, irritability, sleep disorders (in children), nausea, insomnia, exanthema, visual impairment (if in contact with the eyes). Very rarely: fatigue, drowsiness, anxiety, hallucinations, seizures, respiratory arrest (in infants). Prolonged continuous use of vasoconstrictor drugs can lead to tachyphylaxis, atrophy of the nasal mucosa and recurrent swelling of the nasal mucosa (drug-induced rhinitis).

How to take, course of use and dosage

Nasivin® Sensitive nasal spray dosed 22.5 mcg / dose is intended for intranasal use. Adults and children over 6 years of age: 1 injection of Nasivin® Sensitive nasal spray dosed 22.5 mcg / dose in each nostril 2-3 times a day. If symptoms worsen or do not improve within 3 days, you should consult your doctor. At the recommended dose, do not use for more than 7 days without consulting a doctor. Doses higher than recommended should only be administered under medical supervision. One 45 ml injection contains 22.5 mcg of oxymetazoline hydrochloride – for Nasivin® Sensitive nasal spray dosed 22.5 mcg / dose.

Overdose

Symptoms (after a significant overdose or accidental ingestion):

contraction of the pupils, nausea, vomiting, cyanosis, fever, tachycardia, arrhythmia, vascular insufficiency, arterial hypertension, respiratory disorders, pulmonary edema, cardiac arrest; in addition, there may be a mental disorder, and depression of the Central nervous system, accompanied by sleepiness, reduced body temperature, bradycardia, hypotension, respiratory arrest, and possible coma.

Treatment:

gastric lavage, taking activated charcoal, and seeing a doctor immediately.

Description

• Colds or viral infections of the upper respiratory tract accompanied by a runny nose, sinusitis, eustachitis, otitis media, rhinitis of any etiology;
• To eliminate edema before diagnostic manipulations in the nasal passages.

Special instructions

Avoid contact with eyes. To avoid the spread of infection, it is necessary to use the drug individually. After long-term use of cold remedies containing oxymetazoline, in doses exceeding the recommended ones, the overall effect on the cardiovascular system and central nervous system cannot be excluded. In these cases, care should be taken when driving vehicles and engaging in other potentially dangerous activities that require increased concentration of attention and speed of psychomotor reactions.

Form of production

Nasal spray Nasivin Sensitive dosed in the form of a clear or almost transparent solution from almost colorless to slightly yellow.

Storage conditions

At a temperature not exceeding 25 °C.

Shelf

life is 3 years.

Active ingredient

Oxymetazoline

Dosage form

nasal spray

Description

For adults, Nursing mothers as prescribed by a doctor, Children over 6 years old, Pregnant women as prescribed by a doctor

Indications

Sinusitis, Pollinosis, Runny Nose, Allergic Runny Nose, Cold, Otitis Media, Flu