Composition
1 bottle contains:
Active ingredient:
 oxymetazoline hydrochloride 0.025 mg;
Auxiliary substances:
benzalkonium chloride,0.02 g;
camphor racemic — 0.17 g;
the evkaliptola (cineole) — 0.17 g;
levomenthol — 0.17 g;
disodium edetate dihydrate — 0.1 g;
Polysorbate 80 — 0,2 g;
propylene glycol — 10 g;
sodium hydrogen phosphate dihydrate — 0.06 g;
sodium dihydrogen phosphate dihydrate — 0.65 g;
concentrated hydrochloric acid — 0.003 g;
purified water — 89,711 G.
Pharmacological action
Vasoconstrictor drug for topical use in ENT practice.
Oxymetazoline hydrochloride causes narrowing of the vessels of the nasal mucosa, paranasal sinuses and eustachian tube, which reduces their swelling and leads to relief of nasal breathing. Relief of nasal breathing occurs 5-10 minutes after injection into the nasal cavity and lasts up to 12 hours.
Menthol, camphor, eucalyptol have a local decongestant, anti-inflammatory and antiseptic effect, dilute thick mucus and improve its outflow from the paranasal sinuses, as well as increase the duration of the drug’s action.
Indications
-to facilitate nasal breathing in colds and viral infections of the upper respiratory tract, sinusitis, rhinitis of any etiology.
Contraindications
-atrophic rhinitis;
– children under 6 years of age;
— pregnancy;
– lactation;
– hypersensitivity to the components of the drug.
With caution, the drug should be used in patients with diseases of the cardiovascular system (arterial hypertension, coronary heart disease, chronic heart failure, tachycardia, arrhythmias), impaired carbohydrate metabolism (diabetes mellitus), impaired thyroid function (hyperthyroidism), pheochromocytoma, prostatic hyperplasia with clinical symptoms, chronic renal failure, angle-closure glaucoma, with simultaneous use of MAO inhibitors, tricyclic drugs antidepressants.
Side effects
Local reactions: Â sometimes a burning sensation or dryness of the nasal membranes, dryness in the mouth and pharynx, sneezing, an increase in the volume of secretions released from the nose.
In rare cases, after the effect of the drug passes, a strong feeling of “stuffy” nose (reactive hyperemia).
Systemic reactions: Â increased blood pressure, headache, dizziness, palpitations, increased anxiety, nausea, insomnia.
With prolonged use of the drug (more than 7 days), reactive hyperemia of the nasal mucosa, atrophy of the nasal mucosa are possible.
Interaction
When used concomitantly with MAO inhibitors and tricyclic antidepressants, an increase in blood pressure may occur.
The drug slows down the absorption of local anesthetics, prolongs their effect.
Co-use of other vasoconstrictor drugs increases the risk of side effects.
How to take, course of use and dosage
Adults and children over 12 years of age are prescribed 2-3 injections in each nasal passage 2 times/day, children aged 6 to 12 years (under adult supervision) – 1 injection in each nasal passage 2 times/day. Do not use the drug more than 2 times a day.
It is not recommended to use the drug for more than 3 days. With frequent or prolonged use of the drug, the feeling of difficulty in nasal breathing may reappear or worsen. If these symptoms occur, you should stop treatment and consult a doctor.
When injecting, do not tilt your head back or spray while lying down.
Overdose
Symptoms: Â prolonged or frequent use of the drug in the nasal cavity can cause nausea, increased blood pressure, tachycardia, and central nervous system depression.
Treatment: Â conduct symptomatic therapy.
Description
Nasol Advance 10 ml-Nasal spray from the common cold Kanazol Advance is a remedy for the common cold, which, due to the presence of menthol, camphor and eucalyptus in the composition, additionally creates a feeling of freshness and cooling. The features of this tool are: – Relieves nasal congestion in a few minutes-Makes breathing easier for colds and viral infections of the upper respiratory tract, sinusitis, rhinitis of any etiology. – Capable of action for 12 hours
Special instructions
It is not recommended to use Nazol Advance for more than 3 days.
Avoid contact with the eyes. The drug has an effect on vision, possibly reducing the reaction rate.
To avoid the spread of infection, it is necessary to use the drug individually.
Storage conditions
The drug should be stored in a dry place protected from light, out of the reach of children, at a temperature of 2° to 30°C.
Shelf
life is 2 years.
Active ingredient
Oxymetazoline
Dosage form
nasal spray
Description
Children over 6 years old, For adults
Indications
Hay Fever, Runny Nose, Otitis Media, Allergic Rhinitis, Flu, Sinusitis, Cold
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Side effects of Nasol Advance nasal spray 0.025mg/dose, 10ml
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