Nasol Kids nasal spray 0.125mg/dose, 10ml

Composition

100 ml contain:

active substance :

phenylephrine hydrochloride 0.25 g;

excipients :

Benzalkonium chloride 0.018 g,

eucalyptol (cineol) 0.040 g,

glycerol 4,000 g,

macrogol 1500 1,500 g,

sodium hydrophosphate dihydrate 0.226 g,

potassium dihydrogen phosphate 0.101 g,

disodium edetate dihydrate 0.020 g,

purified water 95.845 g

Pharmacological action

Anticongestive agent – alpha-adrenomimetic

Product Code: R01AA04

Pharmacological Properties

A drug for the symptomatic local treatment of rhinitis. Phenylephrine hydrochloride is an alpha-1-adrenergic receptor agonist (sympathomimetic), which has a vasoconstrictive effect by stimulating alpha-1 receptors in the nasal mucosa, reduces mucosal swelling and tissue hyperemia, congestion in the nasal mucosa, and also improves the patency of the nasal airways. Restoration of nasopharyngeal air patency improves the patient’s well-being and reduces the risk of possible complications caused by stagnation of mucosal secretions.

Pharmacokinetics

When applied topically, systemic absorption is low.

Indications

Symptomatic treatment: to facilitate nasal breathing in cases of colds, flu, hay fever or other allergic diseases of the upper respiratory tract, accompanied by acute rhinitis or sinusitis.

Contraindications

• Increased individual sensitivity to the ingredients of the drug,
• diseases of the cardiovascular system (including severe atherosclerosis, angina pectoris, tachycardia)
• diseases of the thyroid gland (thyrotoxicosis)
• diabetes mellitus
• arterial hypertension
• concomitant use of MAO inhibitors (as well as 2 weeks after their withdrawal)
• children under 4 years of age.

Use caution for children under 6 years of age.

Side effects

Local reactions:  burning, tingling, or tingling sensation in the nose.

System effects:  headache, dizziness, palpitations, arrhythmia, high blood pressure, sweating, pallor, tremor, sleep disturbance.

Interaction

Monoamine oxidase inhibitors (procarbazine, selegiline), tricyclic antidepressants, maprotiline, guanedrel, and guanethidine enhance the pressor effect and arrhythmogenicity of phenylephrine (with systemic absorption).

Thyroid hormones with systemic absorption of phenylephrine increase the (mutually) associated risk of coronary insufficiency (especially in coronary atherosclerosis).

How to take, course of use and dosage

Intranasally.

For children aged 6-12 years-2-3 injections in each nasal passage, no more than every 4 hours.

The duration of treatment without consulting a doctor is no more than 3-5 days.

Overdose

It can be manifested by cardiac arrhythmias, increased blood pressure, and agitation.

In case of overdose, you should consult a doctor.

Treatment is symptomatic.

Description

Nasol Kids 10 ml-Nasal spray from the common cold for children aged from 4 letNazol Kids nasal spray from the common cold. The action of the Active ingredient phenylephrine, which is part of the drug Nazol Advance, takes into account the features of a child’s nose in the treatment of a runny nose(1). Suitable for children from 4 years old. The features of this tool are: – Thanks to phenylephrine, it helps to eliminate nasal congestion – Acts gently (1), taking into account the features of the children’s mucosa-Due to the presence of eucalyptus in the composition, it gives an additional feeling of freshness – Facilitates breathing through the nose in colds, flu, hay fever or other allergic diseases of the upper respiratory tract, accompanied by acute rhinitis or sinusitis 1. Karpova E. P., Tulupov D. A. On the safety and effectiveness of nasal vasoconstrictor drugs in pediatric practice. / Voprosy prakticheskoi pediatrii [Questions of Practical pediatrics],2010, vol. 5, no. 5, p. 6569. Phenylephrine has a selective agonism to 1-adrenergic receptors, has a mild vasoconstrictor effect, presumably due to the predominant effect on the obturator choke vessels (superficial arterioles, nasal mucosa), and does not cause a significant decrease in blood flow in it.

Special instructions

In children, systemic absorption of phenylephrine and the associated risk of side effects are higher than in adults. The duration of use of the drug should not exceed 3 days, while maintaining nasal breathing difficulties, further use of the drug should be agreed with the doctor.

Phenylephrine should not be prescribed to patients within 2 weeks after discontinuation of monoamine oxidase inhibitors, as they may increase the severity of the adrenergic effects of sympathomimetic agents and increase the risk of side effects from the cardiovascular system.

It is not recommended to use the same bottle for several people, in order to avoid the spread of infection. When the bottle is compressed in an upright position, the solution is released from it in the form of a spray, when the bottle is compressed in an inverted position – drop by drop.

Impact on the ability to drive and use machinery

There are no data on the negative effect of the drug on the ability to drive a car or other vehicles. However, if you experience symptoms of a side effect of the drug, you should refrain from driving vehicles and performing actions that require concentration or psychomotor reactions.

Form of production

Clear solution of colorless to light yellow color with a faint smell of eucalyptus.

Storage conditions

 In a dark place, at a temperature not exceeding 25 °C.

Shelf life

2 years

Active ingredient

Phenylephrine

Dosage form

nasal spray

Description

Children over 4 years old

Indications

Flu, Cold, Runny Nose, Allergic Runny Nose, Pollinosis, Sinusitis