ATC code | D11AX01 |
---|---|
Other product names | Tacrolimus ointment |
Dosage form | Ointment |
Active ingredient | Tacrolimus |
Pharmacological classification | Topical immunosuppressant |
Pharmacological action | Inhibits T-cell activation, inhibits cytokine production |
Storage conditions | Store at room temperature, avoid direct sunlight |
What is Necrolytic ointment?
Necrolytic ointment: A Topical Treatment for Necrolytic Acral Erythema (NAE)
A topical medicine, necrolytic ointment, contains the potent immunosuppressant tacrolimus. Its main application is in treating a rare skin disorder known as necrolytic acral erythema (NAE).
Sometimes expanding to the ankles, knees, and even the palms, elbows, genitalia, and buttocks, NAE is usually linked with hepatitis C infection and shows as a characteristic, symmetrical rash on the tips of the toes and feet.
Necrolytic ointments Composition
Tacrolimus is the active element of necrolytic ointment, which also contains numerous other components meant to help with application and skin absorption. These comprise purified water, cetostearyl alcohol, macrogol 400, white soft paraffin, polysorbate 60, and propylene glycol.
Necrolytic ointment: Advantages and Effects
Necrolytic ointment reduces the immunological reaction in the damaged skin. The active component, tacrolimus, stops several cytokines that are absolutely essential for T-cell activation from being produced. This helps to lower inflammation and irritation, improving the look of the skin and lowering the burning and itching related to NAE.
Who Should Use Necrolytic ointment?
Which Necrolytic ointment Is Used? Given for
Specifically recommended for the treatment of necrolytic acral erythema (NAE), a skin disorder frequently associated with hepatitis C infection, is necrolytic ointment.
How to Use Necrolytic ointment
Using necrolytic ointment:
Use Necrolytic ointment exactly as directed by your doctor. Your particular need and the degree of your disease will affect the advised dosage and frequency of application.
Necrolytic ointment Dosage and Administration
Your doctor will decide the necessary dosage of necrolytic ointment. Usually, twice daily, a small coating of ointment is dabbed on the afflicted skin patches. Apply the ointment carefully, avoiding touching the mouth, nose, and eyes. After every application, give your hands great attention.
Necrolytic ointment Side Effects and Contraindications
Necrolytic ointment Side Effects
Though they are not felt by everyone, necrolytic ointment may have adverse effects like any drug. Some typical side effects consist in:
- At the application site, burning or stinging feeling
- Skins drying or scaling behavior
- Skin redness or irritability
Less common but yet possible are more severe adverse effects. If you have any unusual or severe adverse effects, stop using it and get the right medical assistance.
Necrolytic ointment: Contraindications
Everybody cannot benefit from necrolytic ointment. Should you be allergic to tacrolimus or any other component in the ointment, you should not use it.
- Have a compromised immune system; either pregnant or nursing
- Have any skin diseases right now?
- Have a history of skin cancer.
Before applying necrolytic ointment, you should talk to your doctor about your medical background and any current illnesses.
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