Norbactin pills 400mg 20pcs

Composition

1 tablet contains norfloxacin 400 mg

Pharmacological action

NORBACTIN has a bactericidal effect.

It acts on the bacterial enzyme DNA gyrase, which provides supercoiling and, thus, stability of bacterial DNA.

Destabilization of the DNA chain leads to the death of bacteria.

It has a wide spectrum of antibacterial action.

Indications

Prevention of infections in patients with granulocytopenia, traveler’s diarrhea.

Bacterial infections of the urinary tract (pyelonephritis, cystitis, urethritis), genitals (prostatitis, cervicitis, endometritis), gastrointestinal tract (salmonellosis, shigellosis), uncomplicated gonorrhea.

Contraindications

It should not be used in patients with severe renal insufficiency (creatinine clearance less than 10 ml / min/1.73 m2) and pregnant women.

It is contraindicated in patients with a history of hypersensitivity to norfloxacin or any other chemical analog.

How to take, course of use and dosage

Acute urinary tract infections – 400 mg twice daily for 7-10 days. Acute uncomplicated cystitis – 400 mg twice a day for 3 days. Recurrent or chronic urinary tract infections with exacerbations – 400 mg twice a day for 4 weeks, then, if necessary,400 mg per day for up to 12 weeks. There is evidence of a significant reduction in the frequency of recurrent urinary tract infections in women with frequent recurrent infections with prophylactic use of 200 mg of Norbactin once after sexual intercourse. Chemoprophylaxis for urological interventions, operations and postoperative infections – 400 mg twice a day before and after surgery, as needed. Acute uncomplicated gonococcal infections-800 mg once. Bacterial intestinal infections – 400 mg twice a day for 5 days. Prevention of travelers ‘ diarrhea-400 mg once a day (no more than 21 days). The widespread use of antibacterial agents for the prevention of diarrhea is not recommended, they can be used in high-risk areas, in the presence of aggravating factors (hypochlorhydria, the use of antacids and secretion inhibitors, dishammaglobulinemia) and a high risk of complications due to dehydration in somatic diseases, taking diuretics, cardiac glycosides. For better efficacy and tolerability, Norbactin should be taken one hour before or two hours after a meal. It should not be taken together with antacids. Patients are advised to drink enough fluids to prevent crystalluria. Patients with renal insufficiency (creatinine clearance from 10 to 30 ml / min/1.73 m2) – 400 mg once a day.

Special instructions

Norbactin should be taken at least 2 hours before or 2 hours after taking antacids or preparations containing iron, zinc, magnesium, calcium or sucralfate.

Norbactin should be used with caution in patients with epilepsy, convulsive syndrome of other etiologies, with severe renal and hepatic impairment. During the treatment period, patients should receive a sufficient amount of fluid (under the control of diuresis).

Form of production

Pills.

Active ingredient

Norfloxacin

Conditions of release from pharmacies

By prescription

Dosage form

Tablets

Description

For adults as directed by your doctor

Indications

Salmonellosis, Female Genital infections, Urinary Tract Infections, Enteritis, Prostatitis, Urethritis, Diarrhea, Intestinal infections