Normax, pills 400mg, 6pcs

Composition

1 tablet contains:

Active ingredient:

norfloxacin 400 mg.

Auxiliary substances:

microcrystalline cellulose,

purified talc,

starch glycolates sodium salt,

colloidal silicon dioxide,

sodium lauryl sulfate,

magnesium stearate,

hydroxypropylmethylcellulose,

titanium dioxide.

Pharmacological action

Normax (norfloxacin) is an antibacterial drug from the group of fluoroquinolones. It has a wide spectrum of bactericidal action.

Highly active against gram-negative bacteria:  Escherichia coli, Haemophilus influenzae, Haemophilus ducreyi, Klebsiella spp. (including Klebsiella pneumoniae), Morganella morganii, Neisseria spp. (including Neisseria gonorrhoeae), Salmonella spp., Shigella spp., Proteus spp., Pseudomonas aeruginosa, Enterobacter spp., Chlamydia trachomatis, Citrobacter freundii, Serratia spp., Yersinia spp.

Active against gram-positive bacteria: Staphylococcus aureus (including penicillinase-producing strains and methicillin-resistant strains), Staphylococcus epidermidis, Staphylococcus saprophyticus, and some strains of Streptococcus spp.

They are not very sensitive to the drug Enterococcus spp. and Acinetobacter spp.

Indications

Acute and chronic urinary tract infections (including pyelonephritis, cystitis, urethritis), genital infections (including chronic prostatitis, cervicitis, endometritis), uncomplicated gonorrhea, gastrointestinal tract (including salmonellosis, shigellosis); prevention of infections in patients with granulocytopenia, intestinal infections

Contraindications

Hypersensitivity (including in the anamnesis), tendinitis or tendon rupture associated with taking norfloxacin or other DRUGS from the quinolone group; glucose-6-phosphate dehydrogenase deficiency, children and adolescents under 18 years of age, for drops-up to 12 years (the safety and efficacy of norfloxacin in children and adolescents have not been determined; it should be borne in mind that norfloxacin causes arthropathy in immature animals).

Side effects

System effects

From the digestive tract:  decreased appetite, nausea, vomiting, bitterness in the mouth (including after instillation in the eye), abdominal pain, diarrhea, increased activity of hepatic transaminases, ALP, LDH; pseudomembranous colitis (with prolonged use).

From the genitourinary system:  crystalluria, glomerulonephritis, dysuria, polyuria, albuminuria, hypercreatininemia, urethral bleeding.

Nervous system and sensory disorders:  headache, dizziness, insomnia, hallucinations, fainting states.

Cardiovascular and blood disorders (hematopoiesis, hemostasis):  tachycardia, abnormal heart rate, decreased blood pressure Blood pressure, vasculitis, leukopenia, eosinophilia, decreased hematocrit.

From the musculoskeletal system:  tendinitis, tendon rupture, arthralgia.

Allergic reactions:  pruritus, urticaria, edema, Stevens-Johnson syndrome.

Other services:  candidiasis.

When instilling in the eye:  visual disturbances, burning and pain in the eye, conjunctival hyperemia, chemosis, photophobia, allergic reactions.

Interaction

With simultaneous use of Normax and warfarin, the anticoagulant effect of the latter increases.

With simultaneous use of Normax and cyclosporine, an increase in the concentration of the latter in blood plasma is noted.

When Normax is co-administered with antacids or preparations containing iron, magnesium, calcium, zinc, sucralfate, norfloxacin absorption decreases due to the formation of complexes with metal ions.

Pharmaceutical interaction

Norfloxacin solution is incompatible with medicinal products with a pH value of 3-4, which are physically or chemically unstable.

How to take, course of use and dosage

Normax is taken orally at 400 mg 2 times a day.

For severe infections, the single dose can be increased to 800 mg.

The duration of treatment is determined individually. The minimum course of treatment is 3 days.

Special instructions

Normax should be used with caution in patients with epilepsy, convulsive syndrome of other etiologies, severe liver and/or kidney function disorders.

The drug should be taken at least 2 hours before or 2 hours after taking antacids or preparations containing iron, magnesium, zinc or sucralfate.

Form of production

Tablets

Storage conditions

Store in a dry place, protected from light, at temperatures below 25 °C

Shelf life

3 years

Active ingredient

Norfloxacin

Conditions of release from pharmacies

By prescription

Dosage form

Tablets

Description

Children over 15 years of age, Children as prescribed by a doctor, Adults as prescribed by a doctor

Indications

Sinusitis, Prostatitis, Diarrhea, Sinusitis, Intestinal infections, Urinary tract infections, Urethritis, Salmonellosis, Adnexitis, Enteritis, Inflammation of the female genital organs