Nutriflex 48/150 lipid emulsion for infusion 1250ml containers, 5pcs

Composition

Isoleucine, leucine, lysine hydrochloride, methionine, phenylalanine, threonine, tryptophan, valine, arginine, and monoglutamate, histidine hydrochloride monohydrate, alanine, aspartic acid, glutamic acid, glycine, Proline, serine, soybean oil, medium chain triglycerides, magnesium acetate Tetra hydrate, sodium acetate trihydrate, sodium dihydrogen phosphate dihydrate, potassium acetate, sodium hydroxide, glucose monohydrate, sodium chloride, calcium chloride dihydrate, zinc acetate, electrolytes: sodium, potassium, calcium, magnesium, zinc, chloride, phosphate, and acetate.

Pharmacological action

Nutriflex 48/150 lipid is a three-chamber system for parenteral nutrition.

System Nutriflex lipid perfectly matches modern approaches to parenteral nutrition. The unique physiological balance of protein, non-protein calories, and fluid achieved in Nutriflex Lipid bags provides the doctor with a comprehensive solution to the problem of nutritional support, and the variety of solutions offered in terms of concentration and volume allows you to meet the needs of almost all patients in various clinical situations.

Advantages of three-chamber NUTRIFLEX lipid bags

• High security, reliability and ease of use
• The possibility of an individual approach is provided by various bag options
• The optimal concentration of amino acids allows you to introduce a sufficient amount of protein without the risk of overfeeding
• A balanced glucose level prevents the development of hyperglycemia in the patient
• Fast, safe and complete fat absorption, thanks to the presence of Lipofundin MCT/LST
• Activation of the wound healing process thanks to zinc, which is contained in a physiological concentration
• Meeting the basic need for electrolytes

Indications

Filling the daily requirement for energy, essential fatty acids, amino acids, electrolytes and water with parenteral nutrition

Contraindications

The drug should not be prescribed for the following conditions: :

• Disorders of amino acid metabolism
• Disorders of fat metabolism
• Hyperkalemia, hypernatremia
• Severe metabolic disorders (ketoacidosis, coma of unknown etiology)
• Severe hyperglycemia, uncorrected by insulin doses up to 6 units / hour
• Acidosis
• Intrahepatic cholestasis
• Severe liver and kidney failure
• Severe heart failure
• Hemorrhagic diathesis
• Acute phase of myocardial infarction
• Acute cases of thromboembolism, fat embolism
• Identified hypersensitivity to egg or soy protein, nut oil, or any of the excipients

General contraindications for parenteral nutrition:

• Severe circulatory disorders (collapse and shock)
• Severe tissue hypoxia
• Hyperhydration states
• Violations of the water-electrolyte balance
• Acute pulmonary edema, decompensated heart failure

How to take, course of use and dosage

It is intended for intravenous use into peripheral and central veins. The temperature of the introduced emulsion should correspond to room temperature. The configuration of the Nutriflex lipid product chambers allows you to add the fat emulsion last, in order to pre-evaluate compatibility with other added drugs. Method for mixing the contents of container chambersIf it is necessary to add other medications to the Nutriflex lipid preparation, use the following method:

If there is no need to add other medications to the Nutriflex lipid preparation, use the following method:

To perform an infusion after mixing the contents of the container chambers:

• After moving the emulsion to the lower chamber, fold the container along the middle line separating the empty upper chambers from the lower one.
• Hang the container on the infusion rack by a special ring in the center of the container.
• Remove the white protective cap from the infusion port, connect the intravenous infusion system and start the infusion at the rate indicated in these instructions for use.

Doses: They are selected according to individual needs. Children from 14 years of age and adultsThe maximum daily dose is 40 ml / kg of body weight, which corresponds

• to 1.28 g of amino acids/kg of body weight/ci,
• 2.56 g of glucose/kg of body weight/ci,
• 1.6 g of fat/kg of body weight/ci.

Children from 2 to 14 years oldThese recommendations are based on average needs. The dose should be individually adapted depending on the age, stage of development and severity of the disease. To calculate the dose, it is necessary to take into account the degree of hydration of paediatric patients. For children, it may be necessary to start therapeutic nutrition with half the calculated dose. The dose should be increased to the maximum in stages according to the individual metabolic capabilities of the body. For children from 2 to 5 years of age, the daily dose is 45 ml / kg of body weight, which corresponds

• to 1.44 g of amino acids/kg of body weight/ci,
• 2.88 g of glucose/kg of body weight/ci,
• 1.8 g of fat/kg of body weight/ci.

For children from 5 to 14 years of age, the daily dose is 30 ml / kg of body weight, which corresponds

• to 0.96 g of amino acids/kg of body weight/ci,
• 1.92 g of glucose/kg of body weight/ci,
• 1.20 g of fat/kg of body weight/ci.

Due to the age characteristics of children, Nutriflex lipid may not fully meet the energy requirement. In these cases, a glucose solution or fat emulsion can be added to the parenteral nutrition program as needed. Introduction rateLong-term use of Nutriflex lipid is recommended. A gradual increase in the infusion rate during the first 30 minutes reduces the incidence of possible complications. The maximum infusion rate is 2.5 ml / kg of body weight / h, which corresponds

• to 0.08 g of amino acids/kg of body weight/h,
• 0.16 g of glucose/kg of body weight/h,
• 0.1 g of fat/kg of body weight/h.

For a patient weighing 70 kg, the maximum infusion rate is 175 ml/h. The rate of introduction of amino acids will be 5.6 g/h, glucose – 11.2 g/h, fat – 7. g/h. Elderly patientsThe doses do not differ from those recommended for other adult patients. However, metabolism can vary significantly in the elderly, so careful monitoring of this group of patients is necessary. Patients with renal and / or hepatic insufficiencyDoses are selected individually. Duration of application The use of Nutriflex lipid is not recommended for more than seven days.

Form of production

Emulsion for infusions

Storage conditions

In a dark place, at a temperature not exceeding 25 °C.

Shelf life

2 years

Active ingredient

Amino acids for parenteral nutrition, Other preparations Minerals

Conditions of release from pharmacies

By prescription

Dosage form

emulsion for infusions