Nutriflex 48/150 lipid emulsion for infusion 2000ml containers, 5pcs

Composition

Emulsion for infusions – solutions of amino acids and glucose with electrolytes: clear, pale yellow or yellow solutions; fat emulsion: an oil-in-water emulsion of milky white color.

Excipients: citric acid monohydrate 0-0.336 g, glycerol 5 g, egg lecithin 2.4 g, sodium oleate 0.06 g, water for injection-up to 1000 ml.

Osmolality: 1540 mOsm / kg. pH: 5.0-6.0.

Pharmacological action

Nutriflex 48/150 – means for parenteral nutrition. Nutriflex contains in one chamber of the bag amino acids, which are a substrate for protein synthesis and minerals necessary for maintaining water-electrolyte and acid-base equilibrium, and in the second chamber – a glucose solution with electrolyte solutions.

Indications

It is used for parenteral nutrition to cover the daily needs of patients for energy, amino acids, electrolytes and fluids in patients with moderate to severe catabolism, in cases where enteral nutrition is impossible, insufficient or contraindicated.

Contraindications

• violation of amino acid metabolism;
• hyperkalemia;
• hyponatremia;
• metabolic disorders (for example, in diabetes mellitus);
• coma of unclear etiology;
• hyperglycemia, uncorrected by insulin doses up to 6 units/h;
• acidosis;
• severe hepatic and/or renal failure;
• children under 2 years of age;
• individual intolerance to one of the components of the mixture.

Common for parenteral nutrition:

• severe circulatory disorders (collapse and shock);
• severe tissue hypoxia;
• hyperhydration;
• impaired water and electrolyte balance;
• pulmonary edema;
• decompensated heart failure.

Side effects

Side effects are very rare. When therapy is discontinued, they are quickly reversible. use of the drug may lead to allergic reactions, chills, nausea, vomiting. Due to the high osmolarity of the solution, signs of increased diuresis may appear in some cases. In such cases, the drug should be discontinued and resumed later at a slower infusion rate. In case of side effects that are not described in the instructions, patients should inform their doctor about them.

How to take, course of use and dosage

Nutriflex 48/150 is intended for use only in the central veins.

Method of preparing Nutriflex 48/150 for use:

Nutriflex 48/150 is a two-chamber bag, the compartments of which are separated by a special seam. One chamber is filled with a solution of amino acids and electrolytes, and the other with a solution of dextrose and electrolytes. Immediately before starting parenteral use, solutions of amino acids, glucose and electrolytes should be mixed. To do this, you need to:

• remove the two-chamber bag from the protective packaging,
• unfold and spread it on a flat surface (on a table),
• tear the separation seam by pressing two hands on one of the bag chambers,
• pick up and mix the contents of both chambers, moving the right and left parts of the bag up and down.

After that, the solution is ready for use. At the end of the infusion, the bag is discarded.

If necessary, lipid emulsions can be added to Nutriflex 48/150 by injecting them into the finished solution through a special port located on the top of the bag. If you need to add other ingredients to the finished solution, use the additional port located at the bottom. All ingredients must be added in compliance with the rules of asepsis and taking into account their compatibility with each other.

Doses:

They are selected according to individual needs. The maximum daily dose is 40 ml / kg mt / day, which corresponds to 1.92 g of amino acids/kg mt/day and 6 g of glucose /kg mt/day.

Introduction rate:

The maximum infusion rate is 2 ml / kg mt / h, which corresponds to 0.096 g of amino acids / kg mt/h and 0.3 g of glucose/kg mt/h.

Duration of application:

There are no restrictions on the duration of use of the drug.

Precautions when using the drug:

In patients with increased plasma osmolarity, with heart failure, with hepatic and / or renal insufficiency. For patients with cardiac, hepatic and renal insufficiency, the dosage and mode of use of the drug are set individually.

Storage conditions

In a dark place, at a temperature not exceeding 25 °C.

Shelf life

2 years

Active ingredient

Amino acids for parenteral nutrition

Conditions of release from pharmacies

By prescription

Dosage form

infusion solution