Composition
Active ingredients:
nystatin 500,000 UNITS
Auxiliary substances:
propyl ether of paraoxybenzoic acid,
food grade citric acid,
vaseline oil,
vitepsol H-15,
vitepsol W-35.
Pharmacological action
Nystatin is a fungistatic substance.
Binding to sterols in the cell wall of fungi, it disrupts its permeability, which leads to the release of the main components of the cell.
Active against yeast-like fungi of the genus Candida, including Candida albicans. It does not have cumulative properties.
Pharmacokinetics
Poorly absorbed from the gastrointestinal tract.
The bulk of the drug taken orally is excreted in the feces. When applied topically, it is not absorbed through the mucous membranes.
Indications
- candidiasis of the lower intestines;
- prevention of fungal lesions in the pre-and postoperative periods.
Contraindications
- liver function disorders;
- pancreatitis;
- peptic ulcer of the stomach and duodenum;
- pregnancy;
- hypersensitivity to the components of the drug.
Side effects
From the digestive system: Â when taking the drug inside and using rectal suppositories, nausea, vomiting, and diarrhea are possible.
Allergic reactions: Â skin pruritus, chills, fever.
Other services: Â there may be a risk of spreading resistant forms of fungi, which requires discontinuation of the drug.
How to take, course of use and dosage
Suppositories are inserted deep into the rectum 1 suppository 2 times a day (morning and evening). The course of treatment is 10-14 days.
If necessary, repeat courses of treatment are carried out.
Form of production
rectal suppositories
Storage conditions
Store in a dry place, protected from light, at a temperature not exceeding 5 °C
Shelf life
2 years
Active ingredient
Nystatin
Conditions of release from pharmacies
By prescription
Dosage form
rectal suppositories
Description
Adult Doctor’s prescription
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Side effects of Nystatin, rectal suppositories 500000 units, 10pcs.
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