Indications
- Acromegaly — to control the main manifestations of the disease and reduce the level of growth hormone and IGF-1 in plasma in cases where there is no sufficient effect from surgical treatment or radiation therapy. Octreotide indicated for the treatment of patients with acromegaly who refused surgery or contraindications to it, as well as for short-term treatment in the intervals between courses of radiation therapy until fully developing its effect;
- – secreting endocrine tumors of the gastrointestinal tract and the pancreas — to control symptoms: carcinoid tumors with the presence of carcinoid syndrome; Vipoma; glucagonoma; gastrinoma syndrome of zollingerellison — usually in combination with proton pump inhibitors and histamine H2-receptors; the insulinoma (to control hypoglycemia in the preoperative period, as well as for maintenance therapy); somatoliberin (tumor, characterized by the overproduction releasing factor growth hormone).
- stopping bleeding and preventing recurrent bleeding from varicose veins of the esophagus and stomach in patients with cirrhosis of the liver. Octreotide is used in combination with specific therapeutic measures, such as endoscopic sclerosing therapy.
The drug is not an antitumor agent and its use cannot lead to a cure for this category of patients.
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