Odeston, pills 200mg, 50pcs

Composition

>

of 1 tab. contains:

Active ingredients: Hymecromone 200 mg

Excipients: potato starch-45 mg, gelatin-3 mg, sodium lauryl sulfate-1 mg, magnesium stearate-1 mg

Pharmacological action

Choleretic drug. Increases the formation and excretion of bile. It has a selective antispasmodic effect on the bile ducts and sphincter of Oddi. The drug does not reduce gastrointestinal motility and blood pressure.

Reduces stagnation of bile, prevents the crystallization of cholesterol and, thus, the development of cholelithiasis.

Pharmacokinetics

Suction and distribution

After oral use, it is rapidly absorbed from the gastrointestinal tract. Cmax in the blood after oral use is reached in 2-3 hours. Weakly binds to plasma proteins.

Excretion

T1 / 2 is about 1 h. It is excreted in the urine: about 93% – in the form of glucuronate,1.4% – in the form of sulfonate,0.3% – unchanged.

Indications

• biliary dyskinesia and Oddi sphincter of hyperkinetic type;
• non-calculous chronic cholecystitis, cholangitis, cholelithiasis;
• condition after surgical interventions on the gallbladder and biliary tract;
• decreased appetite, nausea, constipation, vomiting (against the background of bile hyposecretion).

Contraindications

• hypersensitivity;
• biliary tract obstruction;
• renal / hepatic insufficiency;
• ulcerative colitis, Crohn’s disease;
• peptic ulcer of the stomach and duodenum;
• hemophilia;
• children under 18 years of age.

Side effects

From the digestive system: diarrhea, flatulence, abdominal pain, ulceration of the gastrointestinal mucosa.

Other: allergic reactions, headache.

Interaction

With simultaneous use, morphine, which causes spasm of the sphincter of Oddi, weakens the effect of Odeston.

With the simultaneous use of Odeston with metoclopramide, there is a mutual weakening of the action.

Odeston enhances the effects of indirect anticoagulants.

How to take, course of use and dosage

The drug is administered orally 30 minutes before meals.

Adults are prescribed 200-400 mg 3 times a day. The daily dose is 1200 mg. The course of treatment is 2 weeks.

If you miss a dose, you should take the drug as soon as possible. If the time for the next dose is approaching, do not take the missed dose. Do not take a double dose of the drug to compensate for the missed one.

Overdose

Currently, no overdose cases of Odeston have been reported.

Special instructions

Special precautions when disposing of an unused medicinal product

Do not dispose of medicines in the sewer system or in household waste containers. Please contact your pharmacist for instructions on how to dispose of unused medication. These activities will help protect the environment.

Influence on the ability to drive motor vehicles and manage mechanisms

The drug does not affect the ability to drive vehicles and engage in other potentially dangerous activities that require increased concentration of attention and speed of psychomotor reactions.

Form of production

Tablets

Storage conditions

At a temperature not exceeding 25 °C

Shelf life

3 years

Active ingredient

Gimecromon

Dosage form

Tablets

Description

Pregnant women as prescribed by a doctor, Nursing mothers as prescribed by a doctor, For adults

Indications

Cholelithiasis, Biliary dyskinesia, Cholecystitis