Pharmacological action
Pharmacokinetics When applied to the nails, it penetrates the nail plate and further into the nail bed, almost completely within the first 24 hours. The effective concentration remains in the affected nail plate for 7-10 days after the first application. Systemic absorption is insignificant: the plasma concentration is below the sensitivity limit of the determination methods (less than 0.5 ng / ml).
Indications
-Treatment of fungal nail lesions caused by dermatophytes, yeast and mold fungi; – prevention of fungal nail lesions.
Contraindications
Hypersensitivity to Amorolfine and other components of the drug. Under 18 years of age.
Description
Onychelp varnish is a drug that is applied directly to the nail plate. It acts locally, destroying the mycelium and spores of the fungus in the nail, prevents the spread of the fungus to neighboring nails and prevents re-infection. Antimycotic Amorolfine, which is part of Onychelp varnish, causes damage to the cytoplasmic membranes in the cells of pathogenic fungi, which causes their death. Antifungal drug for external use. It has a fungistatic and fungicidal effect due to damage to the cytoplasmic membrane of the fungus by disrupting the biosynthesis of sterols. The content of ergosterol decreases, and the content of atypical steric non-planar sterols accumulates.
Active ingredient
Amorolfine
Description
For adults
Indications
Nail Fungus
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Side effects of Onyhelp nail polish 5%, 5ml
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