Composition
1 capsule. contains: Active ingredients: Â orlistat (substance-pellets 50%) 120 mg. Auxiliary substances: microcrystalline cellulose – 98.64 mg, sodium carboxymethyl starch-10.08 mg, sodium lauryl sulfate-6.24 mg, povidone K 30-5.04 mg.
Capsule body composition: Â
proprietary blue dye – 0.2786%,
titanium dioxide-2%,
gelatin – up to 100%.
Capsule cap composition: Â
proprietary blue dye – 0.2786%%,
titanium dioxide-2%,
gelatin – up to 100%.
Pharmacological action
Lipase inhibitor. When taken orally, orlistat inhibits gastric and pancreatic lipases. As a result, the breakdown of dietary fats is disrupted and their absorption from the gastrointestinal tract decreases. When used systematically, this effect leads to a decrease in body weight in obese patients. Orlistat is practically not absorbed from the gastrointestinal tract and therefore has practically no resorptive effect.
Indications
Obesity (combined with a moderate-calorie diet).
Contraindications
Chronic malabsorption syndrome, hypersensitivity to orlistat.
Side effects
Possible: Â oily discharge from the rectum, flatulence, ” fat ” stools, frequent defecation, imperative urge to defecate, fecal incontinence.
Interaction
Orlistat has been shown to reduce the absorption of betacarotene and alpha-tocopherol from the gastrointestinal tract.
How to take, course of use and dosage
Take 120 mg orally during each main meal or within an hour after a meal, usually no more than 3 times a day. If the food contains little fat, you can skip taking orlistat.
Special instructions
It should be borne in mind that the frequency and severity of side effects increase with an increase in the content of fat in food. When the fat content in food decreases, the likelihood of side effects decreases. It is recommended that the amount of fat consumed per day is fairly evenly distributed over all meals.
During treatment, as the body weight decreases, it is possible to improve the course of pathological processes often associated with obesity, including arterial hypertension, diabetes mellitus, and lipid metabolism disorders.
Active ingredient
Orlistat
Conditions of release from pharmacies
By prescription
Dosage form
Capsules
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Side effects of Orlistat capsules 60mg 42pcs.
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