Orvis Immuno pills 125mg, 6pcs

Composition

For 1 tablet: Active ingredient: Tilorone dihydrochloride (tilorone) – 125.00 mg. Auxiliary substances: Calcium hydrophosphate (anhydrous double-substituted calcium phosphate) – 78.00 mg; Microcrystalline cellulose-76.00 mg; Croscarmellose sodium-15.00 mg; Povidone K-30-3.00 mg; Magnesium stearate-1.50 mg;Stearic acid -1.50 mg. Shell excipients: Hypromellose (hydroxypropyl methylcellulose) – 6,17 mg;Titanium dioxide – 1,85 mg;Macrogol 4000 (polyethylene glycol 4000) – 1,24 mg;Polysorbate 80 – 0.62 mg;Dye sunset yellow and 0.12 mg

Pharmacological action

Pharmacodynamically synthetic interferon inducer of stimulating education in the body of all types of interferons (alpha, beta, gamma and lambda). The main producers of interferon in response to the introduction of tiloron are intestinal epithelial cells, hepatocytes. T-lymphocytes, neutrophils, and granulocytes. After oral use, the maximum production of interferon is determined in the gut-liver-blood sequence after 4-24 hours. Tiloron has an immunomodulatory and antiviral effect. In human leukocytes, it induces the synthesis of interferon. It stimulates bone marrow stem cells, increases antibody formation, and reduces the degree of immunosuppression depending on the dose. restores the ratio of T-suppressors and T-helpers. It is effective against various viral infections, including influenza viruses, other acute respiratory viral infections, hepatitis viruses and herpesviruses. The mechanism of antiviral action is associated with the inhibition of translation of virus-specific proteins in infected cells, as a result of which viral reproduction is suppressed. Pharmacokineticsafter oral use, it is rapidly absorbed from the gastrointestinal tract. Bioavailability – 60%. About 80% of the drug binds to plasma proteins. The drug is excreted almost unchanged through the intestines (70%) and through the kidneys (9%). The half-life (Half-life) is 48 hours. The drug does not undergo biotransformation and does not accumulate in the body.

Indications

As part of complex therapy in adults:

• Treatment of influenza and other acute respiratory viral infections.
• Treatment of herpes infection.
• Prevention of influenza and acute respiratory viral infections.

Use during pregnancy and lactation

The use of the drug during pregnancy is contraindicated. If it is necessary to use the drug during lactation, breastfeeding should be discontinued.

Contraindications

• Hypersensitivity to tilorone and other components of the drug;
• Pregnancy and breast-feeding period;
• Children under 18 years of age.

Side effects

Possible allergic reactions, dyspeptic phenomena, short-term chills. If any of the side effects listed in the instructions get worse, or you notice any other side effects not listed in the instructions, tell your doctor.

Interaction

It is compatible with antibiotics and drugs for the traditional treatment of viral and bacterial diseases. There was no clinically significant interaction of tilorone with antibiotics and traditional treatment of viral and bacterial diseases, as well as alcohol.

How to take, course of use and dosage

The drug is taken orally, after a meal. For the treatment of influenza and other acute respiratory infections-125 mg per day for the first 2 days of treatment, then 125 mg after 48 hours. For the course-750 mg (6 tablets). For the prevention of influenza and other acute respiratory viral infections-125 mg 1 time a week for 6 weeks. For the course-750 mg (6 tablets). For the treatment of herpetic infection – the first two days of 125 mg, then after 48 hours of 125 mg. The course dose is 1.25-2.5 g (10-20 tablets). In the treatment of influenza and other acute respiratory viral infections, if symptoms persist for more than 4 days, you should consult a doctor.

Overdose

Cases of overdose of the drug are not known.

Special instructions

Influence on the ability to drive vehicles and mechanismsthe drug does not negatively affect the ability to perform potentially dangerous activities that require increased attention and speed of psychomotor reactions (driving a car and other vehicles, working with moving mechanisms, working as a dispatcher, operator, etc. ).

Storage conditions

At a temperature not exceeding 25°C. Keep out of reach of children.

Shelf

life is 3 years.

Active ingredient

Tiloron

Description

Children over 7 years of age, For adults, Children as prescribed by a doctor

Indications

Herpes, Flu and cold prevention, Flu