Otofa, ear drops, 10ml

Composition

100 ml of ear drops contain:

Active ingredient:

rifamycin sodium 2.6 g, which corresponds to 2,000,000 IU;

Auxiliary substances:

macrogol 400-25 g,

ascorbic acid-500 mg,

disodium edetate-12 mg,

potassium disulfite-150 mg,

lithium hydroxide-135 mg,

purified water-up to 100 ml

Pharmacological action

An antibiotic from the rifamycin group for topical use in otorhinolaryngology.

The mechanism of action of rifamycin is associated with the formation of a stable complex with DNA-dependent RNA polymerase, which prevents bacterial growth.

 It is active against most gram-positive and gram-negative bacteria that cause the development of infectious and inflammatory diseases of the outer and middle ear.

Indications

Acute and chronic otitis media:

• otitis externa;
• acute otitis media (including with perforation of the tympanic membrane);
• chronic otitis media;
• conditions after surgery on the middle ear.

Use during pregnancy and lactation

Adequate and strictly controlled clinical studies on the safety of using Otofa during pregnancy and lactation (breastfeeding) have not been conducted.

Contraindications

Hypersensitivity to rifamycin.

Side effects

Pink color of the tympanic membrane (visible on otoscopy).

How to take, course of use and dosage

Otofa is applied topically, instilling in the external ear canal; before use, the bottle is warmed by holding it in your hand.

5 drops (children — 3 drops) 3 times a day or twice a day are poured into the external ear canal for several minutes.

The course lasts 1-3 days (no more).

Special instructions

Rifampicin-resistant strains may occur. Otofa contains sulfites.

Form of production

Ear drops

Storage conditions

At a temperature not exceeding 25 °C

Shelf life

3 years

Active ingredient

Rifamycin

Conditions of release from pharmacies

By prescription

Dosage form

ear drops

Description

Nursing mothers as prescribed by a doctor, Pregnant women as prescribed by a doctor

Indications

Otitis