ATC code | N03AX |
---|---|
Other product names | Pagluferal-3 |
Dosage form | Tablets |
Active ingredient | Bromisovalum, Calcium Gluconate, Caffeine, Papaverine, Phenobarbital |
Pharmacological classification | Antiepileptic |
Pharmacological action | Anticonvulsant, Sedative, Hypnotic |
Storage conditions | Store in a dry place, at room temperature, out of reach of children |
Pagluverine-3: What It Is and How It Works
Pagluverin-3 is a combined antiviral drug used to treat mild to moderate COVID-19 in individuals at high risk for developing severe COVID-19. It contains two antiviral drugs, nirmatrelvir and ritonavir, which work together to stop the SARS-CoV-2 virus from replicating. This means it can help to reduce the severity of COVID-19 symptoms and prevent the illness from progressing to a more critical condition.
Pagluverin-3 Composition
Pagluverin-3 contains two active ingredients:
- Nirmatrelvir: A protease inhibitor that works by blocking the function of a viral enzyme known as SARS-CoV-2 3CL protease. This enzyme is essential for the virus to replicate, so by inhibiting it, nirmatrelvir can effectively prevent the virus from multiplying.
- Ritonavir: Another protease inhibitor that helps to boost nirmatrelvir levels in the body. This ensures that nirmatrelvir is present in sufficient amounts to effectively inhibit viral replication.
Pagluverine-3: Effects and Benefits
Clinical trials have shown that Pagluverin-3 is effective in reducing the severity of COVID-19 symptoms and preventing the illness from progressing to a more severe condition. Compared to a placebo, Pagluverin-3 was shown to reduce the risk of hospitalization or death by 89%.
Its important to understand that Pagluverin-3 is not a cure for COVID-19. It is a treatment that can help to prevent complications and reduce the severity of the illness. Additionally, its crucial to remember that Pagluverin-3 should not be used as a substitute for vaccination. Vaccination remains the best way to prevent COVID-19.
Who Should Take Pagluverine-3?
Pagluverin-3 is used to treat mild to moderate COVID-19 in adults at high risk for severe COVID-19. This includes individuals who are:
- Fifty years of age or older
- Have underlying medical conditions, such as heart disease, diabetes, or obesity.
Pagluverin-3 should be taken within the first five days of developing COVID-19 symptoms.
How to Take Pagluverine-3
Pagluverin-3 is taken orally, either with or without food. The recommended dosage is two tablets (300 mg) of nirmatrelvir and one tablet (100 mg) of ritonavir administered together twice daily for five days.
- Swallow the tablets whole. Do not break, chew, or crush them.
- Take Pagluverin-3 at approximately the same time each day.
- Continue taking Pagluverin-3 for the full duration of treatment, even if you start to feel better. Early cessation of treatment can allow the virus to continue replicating and may increase the risk of complications.
Pagluverin-3 Dose and Administration
The recommended dosage of Pagluverin-3 is two tablets (300 mg) of nirmatrelvir and one tablet (100 mg) of ritonavir administered together twice daily for five days. Swallow the tablets whole. Take Pagluverin-3 at approximately the same time each day. Do not break, chew, or crush the pills. Continue taking Pagluverin-3 for the full duration of treatment, even if you start to feel better. Early cessation of treatment can allow the virus to continue replicating and may increase the risk of complications.
Side Effects of Pagluverine-3
Like all medications, Pagluverin-3 can have side effects. The most common side effects of Pagluverin-3 are:
- Diarrhea
- Bitter or metallic taste in the mouth
- Blood pressure changes
These side effects are usually mild and temporary. However, some individuals may experience more serious side effects, such as:
- Allergic reactions
- Liver problems
- Resistance to HIV infections
If you experience any serious side effects, stop taking Pagluverin-3 and contact your doctor immediately.
Who Should Not Take Pagluverine-3?
Pagluverin-3 is not suitable for everyone. It should not be taken by individuals who:
- Are allergic to nirmatrelvir, ritonavir, or any other ingredient in the medication.
- Are pregnant or breastfeeding, as it is unknown if it is safe for the developing fetus or infant.
- Have certain medical conditions, including liver disease, kidney disease, or HIV infection. Individuals with these conditions should exercise caution when using Pagluverine-3.
Before starting Pagluverine-3, its important to discuss your medical history with your healthcare provider to ensure it is appropriate for you.
Where to Purchase Pagluverine-3
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