Composition
1 suppository contains:
Active ingredient:
mesalazine 1000 mg;
Auxiliary substances:
povidone;
macrogol 6000;
magnesium stearate;
talc.
Pharmacological action
Pentasa is an anti-inflammatory.
Pentasa reduces the formation of leukotrienes and cytokinins, neutralizes free radicals, and inhibits leukocyte chemotaxis.
Indications
Non-specific ulcerative colitis; Crohn’s disease.
Use during pregnancy and lactation
During pregnancy and lactation, it is prescribed only in cases where the positive effect exceeds the risk of possible side effects.
Contraindications
Hypersensitivity (including to salicylates, etc. components of the drug); severe violations of liver and kidney function.
Side effects
Abdominal discomfort, nausea, vomiting, headache, diarrhea, skin rash in the form of urticaria or eczema;
very rarely-muscle and joint pain, temporary hair loss, liver and kidney function disorders, pericarditis, myocarditis, pancreatitis, changes in blood formula (leukopenia, granulocytopenia, thrombocytopenia, anemia).
How to take, course of use and dosage
Rectally, adults — 1 suppository 1-2 times a day in the rectum until the resistance of the muscle pulp stops (before use, the intestines are emptied, the suppository is moistened with water to facilitate use, and a rubber fingertip is used to ensure hygiene).
If the suppository is removed within 10 minutes, another suppository should be inserted.
Special instructions
In some cases of an allergic reaction to sulfasalazine, intolerance to Pentasa may also develop (risk of allergy to salicylates).
Form of production
Suppositories for rectal use
Storage conditions
At a temperature not exceeding 25 °C
Shelf life
3 years
Active ingredient
Mesalazine
Conditions of release from pharmacies
By prescription
Dosage form
rectal suppositories
Description
For adults as directed by your doctor
Indications
Colitis, Crohn ‘s Disease
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Side effects of Pentasa, rectal suppositories 1g, 28pcs.
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