Phencarol, pills 50mg 15pcs

Pharmacological action

Histamine H1-receptor blocker.

Prevents the development and eases the course of allergic reactions.

It has an anti-allergic, anti-exudative and antipruritic effect, preventing the development of allergic inflammation in the tissue.

Weakens the effect of histamine, reduces its effect on vascular permeability (reducing permeability, has an anti-edematous effect), reduces its bronchospastic effect and spasmogenic effect on intestinal smooth muscle, weakens the hypotensive effect of histamine.

Hifenadine reduces the content of histamine in tissues (due to the ability to activate diamine oxidase, an enzyme that inactivates histamine).

During the course of treatment, the antihistamine effect of hifenadine is not reduced.

It has a moderate antiserotonin effect, shows weak m-holinoblokiruyuschuyu activity.

It does not have a depressing effect on the central nervous system.

Indications

-pollinosis;

– acute and chronic urticaria;

– angioedema;

– allergic rhinitis

— – dermatoses (including eczema, psoriasis, atopic dermatitis, pruritus).

Contraindications

-pregnancy;

– lactation (breastfeeding);

– children under 3 years of age (for this dosage form);

– sucrose/isomaltase deficiency, fructose intolerance, glucose / galactose malabsorption, because the drug contains sucrose —

– hypersensitivity to the components of the drug.

Side effects

From the digestive system: dryness of the oral mucosa, nausea, vomiting.

From the central nervous system : drowsiness, headache.

Other: allergic reactions.

Interaction

Having weak m-cholinoblocking properties, the drug can reduce gastrointestinal motility, which contributes to an increase in the absorption of slowly absorbed drugs (for example, indirect anticoagulants-coumarins).

How to take, course of use and dosage

The drug is taken orally after a meal.

  The dosage scheme of the drug coincides with all indications for use.

The dosage of hifenadine may be affected by the severity of the allergic reaction, the individual sensitivity of the patient, as well as the severity of possible side effects.

Adults are prescribed 25-50 mg 3-4 times a day.

The maximum daily dose is 200 mg.

The course of treatment is 10-20 days.

If necessary, the course of treatment is repeated.

Children aged 3 to 7 years – 10 mg 2 times/day; aged 7 to 12 years-10-15 mg 2-3 times/day; older than 12 years-25 mg 2-3 times/day.

The course of treatment is 10-15 days.

Overdose

Symptoms: dry mucous membranes, headache, vomiting, abdominal pain and other symptoms of dyspepsia.

Treatment: gastric lavage, taking activated charcoal, conducting symptomatic therapy.

In case of overdose, the patient should consult a doctor.

Special instructions

With caution, the drug should be prescribed for diseases of the gastrointestinal tract, liver and kidneys.

  The absence of a pronounced m-holinoblocking effect allows prescribing the drug to patients who are contraindicated in antihistamines with m-holinoblocking activity.

Storage conditions

 In a dark place, at a temperature not exceeding 25 °C.

Shelf

life is 4 years.

Active ingredient

Hifenadine

Dosage form

Tablets

Description

For adults

Indications

Psoriasis, Eczema, Allergic Rhinitis, Neurodermatitis, Pollinosis, Allergy, Dermatosis, Urticaria