Composition
Active ingredient:
piroxecam
Pharmacological action
Piroxicam – analgesic, antipyretic, anti-inflammatory.
Selectively inhibits cyclooxygenase, disrupts arachidonic acid metabolism, and reduces the formation of PG.
Relieves or eliminates moderate-intensity pain, reduces the severity of inflammation, reduces morning stiffness of the joints in case of joint syndrome, and helps to increase the volume of movement. The full therapeutic effect appears after 10-14 days of application.
Indications
Rheumatoid arthritis, osteoarthritis, spondylitis, acute gout attack, inflammatory diseases of the musculoskeletal system.
Use during pregnancy and lactation
Piroxicam is contraindicated for use during pregnancy and lactation.
Contraindications
Hypersensitivity, including to NSAIDs, peptic ulcer disease, hematopoietic disorders, liver and kidney diseases, cardiovascular insufficiency, bronchial asthma, pregnancy, breast-feeding (stop breastfeeding).
Side effects
Erosive and ulcerative lesions of the gastrointestinal tract, edema, headache, dizziness, drowsiness, allergic skin reactions.
Interaction
Enhances the effect of oral anticoagulants, increases the concentration of lithium salts in the blood.
Alcohol increases the likelihood of side effects.
The level in the blood is reduced by derivatives of salicylic acid.
How to take, course of use and dosage
Inside,20-40 mg per day in 1-2 doses.
Overdose
Symptoms: nausea, vomiting (with high doses – bloody), melena, meniere’s-like phenomena, tinnitus, clonic and tonic convulsions, coma, hemorrhagic diathesis, agranulocytosis, aplastic anemia, petechial or bullous rash, urticaria, cortex – or typhoid-like rashes; in predisposed patients – toxic-allergic shock.
Treatment: carried out according to the generally accepted principles of clinical toxicology.
Special instructions
Patients with impaired gastrointestinal function, after extensive surgical interventions, in the elderly, patients with bronchial asthma and a history of chronic bronchospastic diseases should monitor the blood cell composition, kidney and liver function.
In women, the contraceptive effect of IUD may decrease due to the effect of piroxicam on myometrial tone. Recommendations for use in children are currently not developed. During treatment, the use of ethanol should be excluded.
Do not apply on damaged skin. Avoid contact with eyes or mucous membranes.
During the treatment period, care should be taken when driving vehicles and doing other activities. potentially dangerous activities that require increased concentration of attention and speed of psychomotor reactions.
Form of production
Capsules
Storage conditions
Store in a dry place, protected from light, at a temperature not exceeding 25 °C
Shelf life
2 years
Active ingredient
Piroxicam
Conditions of release from pharmacies
By prescription
Dosage form
Capsules
Description
Children over 14 years of age, For adults as prescribed by a doctor
Indications
Osteoarthritis, Tendon Inflammation, Osteoarthritis and Arthritis, Rheumatoid Arthritis, Gout, Osteochondrosis, Periarthritis, Bursitis
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Side effects of Piroxicam, capsules 10mg, 20pcs.
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