Composition
Solution for intramuscular use.
Active ingredient: Â
Polimuramil – 200 mcg.
Auxiliary substances:
water for injection 0.5 ml
Pharmacological action
Immunostimulating agent.
Polimuramil is a natural immunostimulant.
It enhances the uptake of bacteria and the killing of bacteria by phagocytic cells.
This increases the ability of monocytes, macrophages, and dendritic cells to produce cytokines (interleukin-12, tumor necrosis factor-α, granulocyte-macrophage colony-stimulating factor, etc. ) that activate cellular and humoral immunity.
Polimuramil enhances the synthesis of antibodies and increases the functional activity of natural killers that play an important role in antiviral and antitumor immunity.
Polimuramil has no teratogenic, embryotoxic, mutagenic or carcinogenic properties.
Indications
Polimuramil is used in adults simultaneously with antibacterial drugs in complex therapy:
– secondary immunodeficiencies, manifested in the form of chronic, indolent, recurrent infectious and inflammatory processes of the skin and soft tissues;
– acute and chronic pyoderma, of osteopathically, sycosis, deep folliculitis, carbuncle, of hidradenitis, boils, abscesses, impetigo;
– for the treatment and prophylaxis of surgical infections, including postoperative septic complications.
Contraindications
Pregnancy, lactation, and children under 18 years of age.
Side effects
There may be a temporary increase in temperature to 37.5 ° C, chills, soreness at the injection site.
Interaction
The drug is compatible with all antimicrobial and anti-inflammatory drugs.
How to take, course of use and dosage
Polimuramil is administered intramuscularly (iv) at a dose of 200 mcg/0.5 ml daily. In the case of secondary immunodeficiency states-200 mcg / m,1 time a day for 5 days as part of complex therapy with broad-spectrum antibiotics.
In the case of acute and chronic pyoderma in the acute stage (staphyloderma, streptoderma, mixed forms) – 200 mcg / m,1 time a day for 5 days as part of complex therapy with broad-spectrum antibiotics.
In the case of treatment and prevention of surgical infections in the acute stage-200 mcg / m,1 time a day,5 days as part of complex therapy (surgical treatment of a purulent focus, systemic antibacterial therapy, dressings with antiseptic and local antibacterial agents).
Overdose
In case of overdose, an increase in temperature is possible, with febrile values of temperature, symptomatic treatment should be carried out.
Special instructions
The drug does not affect the ability to drive vehicles and other mechanisms.
Storage conditions
Store in a place protected from light and out of reach of children at a temperature of 2 to 8 °C. Do not freeze it.
Shelf
life is 5 years.
Active ingredient
Polimuramil
Conditions of release from pharmacies
By prescription
Dosage form
solution for injection
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Side effects of Polimuramil solution for intramuscular injection 200mg/ml 0.5ml ampoules, 5pcs.
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