Pyo bacteriophage complex liquid vial, 100ml

Composition

The solution contains:

Active ingredients:

a mixture of sterile filtrates of phagolysates of staphylococci,

streptococci,

enterococci,

proteus,

Klebsiella (pneumonia and oxytocci),

Pseudomonas aeruginosa and Escherichia coli 100 ml

Pharmacological action

Pyo bacteriophage liquid complex-a drug with a specific selective antibacterial effect. Pyobacteriophage is active against strains of streptococci, proteus, staphylococci, enterococci, oxytococci, Pseudomonas aeruginosa, Klebsiella pneumoniae and Escherichia coli.

Pyobacteriophage lyses sensitive bacteria due to its ability to attach to their membrane and enter the cell. In a bacterial cell, phage particles multiply due to the energy resources of microorganisms, which leads to their death.

After the death of a bacterial cell, mature phage particles are released that can infect other sensitive microorganisms.

Pyo bacteriophage does not affect other types of bacteria and does not cause violations of the natural microflora.

Indications

Treatment and prevention of purulent-inflammatory and intestinal diseases caused by staphylococci, enterococci, streptococci, Pseudomonas aeruginosa, Klebsiella, pathogenic Escherichia coli of various serogroups, proteus with internal, rectal and external use:

• Diseases of the ear, throat, nose, respiratory tract and lungs: inflammation of the sinuses, middle ear, sore throat, pharyngitis, laryngitis, tracheitis, bronchitis, pneumonia, pleurisy.
• Surgical infections: suppuration of wounds, burns, abscess, phlegmon, boils, carbuncles, hydroadenitis, panaritia, paraproctitis, mastitis, bursitis, osteomyelitis.
• Urogenital infections: urethritis, cystitis, pyelonephritis, colpitis, endometritis, salpingoophoritis.
• Post-traumatic conjunctivitis, keratoconjunctivitis, purulent corneal ulcers and iridocyclitis.
• Enteral infections: gastroenterocolitis, cholecystitis, dysbiosis.
• Generalized septic diseases.
• Purulent-inflammatory diseases of newborns: omphalitis, pyoderma, conjunctivitis, gastroenterocolitis, sepsis, etc..
• Other diseases caused by Staphylococci, streptococci, enterococci, Proteus, Klebsiella pneumoniae and oxytocci, Pseudomonas aeruginosa and Escherichia coli.

For preventive purposes, the drug is used for the treatment of operating rooms and freshly infected wounds, as well as for the prevention of nosocomial infections for epidemic indications.

An important condition for effective phage therapy is a preliminary determination of the phage sensitivity of the pathogen.

Use during pregnancy and lactation

During pregnancy, as well as breast-feeding, the drug Pyo bacteriophage can be prescribed by the attending physician.

Contraindications

Missing items.

Side effects

When using the drug Pyo bacteriophage, no undesirable effects were observed.

Interaction

The drug can be used in combination with other medications, including antibiotics.

How to take, course of use and dosage

Pyo bacteriophage is intended for topical and oral use, as well as for rectal use.

Treatment of purulent-inflammatory processes is recommended by simultaneous topical application and oral use of the drug Pyo bacteriophage.

Depending on the location of the infection, Pyo bacteriophage is recommended for:

1. Topical application in the form of lotions, sprays, applications and swabs, moistened solutions. In this case, use the required amount of solution, based on the size of the affected area. In abscesses, the solution should be inserted into the cavity after removal of pus by puncture (the volume of the solution should be slightly less than the volume of extracted pus).2. Introduction of the solution into the pleural, articular and other restricted cavities. After maintaining the required amount of bacteriophage, capillary drainage is left, through which repeated doses of the drug are subsequently administered. 3. Introduction of the solution into the drained cavity of the bladder and renal pelvis through a cystostomy or nephrostomy. 4. Introduction of the solution into the uterine or vaginal cavity, including in the form of tampons soaked in the solution. 5. Instillation, washing and rinsing, as well as the introduction of turundum moistened with a solution, in otolaryngological practice. 6. Introduction to the conjunctival sac in ophthalmological practice. 7. Introduction of moistened turundum into periodontal pockets in dental practice. 8. Introduction to the rectum in the form of enemas in gastroenterological practice. The dose of Pyo bacteriophage and the duration of therapy is determined by the doctor.

The single dose recommended for children under 6 months is 5 ml when administered orally or 10 ml when administered rectally. The single dose recommended for children 6-12 months is 10 ml for oral use and 20 ml for rectal use. The single dose recommended for children 1-3 years of age is 15 ml for oral use and 30 ml for rectal use. The single dose recommended for children 3-8 years is 20 ml when administered orally and 40 ml when administered rectally. The single dose recommended for children from 8 years of age and adults is 30 ml for oral use and 50 ml for rectal use. In the treatment of purulent-inflammatory diseases and intestinal diseases, as a rule, the appropriate single dose is prescribed three times a day.

If the wound was previously treated with an antiseptic during topical use of the bacteriophage, it is necessary to wash the wound with 0.9% sodium chloride solution before using the Pyo bacteriophage solution.

Children under 6 months of age with enterocolitis and sepsis, Pyo bacteriophage solution is administered in the form of high enemas twice or three times a day. If the child does not develop regurgitation and vomiting, the drug can be given orally.

The average duration of the course of therapy is from 5 to 15 days.

As a preventive measure, the drug is prescribed in a single dose twice a day for 5-7 days.

Overdose

Measures to help with overdose have not been established.

Special instructions

Before use, the bottle with the liquid bacteriophage must be shaken. In case of turbidity, do not use!

Form of production

Solution for oral use and topical application.

Storage conditions

Store in a dry place, protected from light, at a temperature of 2-8 °C

Shelf life

2 years

Active ingredient

Pyobacteriophage

Dosage form

solution for oral use

Description

Children as prescribed by a doctor, Adults as prescribed by a doctor

Indications

Bursitis, Enteritis, Boils, Respiratory Tract Infections, Dysbiosis, Osteomyelitis, Urethritis, Colds, Pneumonia, Tracheitis, Cholecystitis, Purulent wounds, Bronchitis