Ranavexim powder for external use, 5g

Composition

Active ingredient: Sulfonamide (streptocide) – 5 g

Pharmacological action

Sulfonamide is an antimicrobial bacteriostatic agent. The mechanism of action is associated with competitive antagonism with paraaminobenzoic acid (PABA) and inhibition of dihydropteroate synthetase, which leads to disruption of the synthesis of dihydrofolic acid, and then tetrahydrofolic acid, as a result of which the synthesis of nucleic acids of microorganisms is disrupted. Active against gram-positive and Gram-negative microorganisms: Escherichia coli, Shigella spp., Vibrio cholerae, Clostridium spp., Bacillus anthracis, Corynebacterium diphtheriae, Yersinia pestis, Chlamydia spp., Actinomyces spp., Toxoplasma gondii.

Indications

As part of complex therapy: purulent wounds, infected burns (I-II stages) and other purulent-inflammatory processes of soft tissues.

Use during pregnancy and lactation

It is contraindicated for use during pregnancy and lactation.

Contraindications

Hypersensitivity to sulfonamides, diseases of the hematopoietic system, inhibition of bone marrow hematopoiesis, anemia, chronic heart failure, thyrotoxicosis, renal / hepatic insufficiency, azotemia, porphyria, congenital glucose-6-phosphate dehydrogenase deficiency, pregnancy, breastfeeding.

Use caution

for children under 3 years of age.

Side effects

With hypersensitivity to sulfonamide agents, allergic reactions are possible, the development of which requires immediate discontinuation of the drug. In addition, headache, dizziness, nausea, vomiting, dyspepsia, cyanosis, leukopenia, agranulocytosis, crystalluria are possible. If any of the side effects listed in the instructions get worse, or you notice any other side effects not listed in the instructions, tell your doctor.

Interaction

Myelotoxic drugs increase the manifestations of hematotoxicity of the drug.

How to take, course of use and dosage

Externally, in the form of powder for external use, it is applied directly to the affected surface; dressings are carried out after 1-2 days. Maximum doses for adults: single dose – 5 g, daily dose – 15 g. For children over 3 years of age: single dose-300 mg, daily dose-300 mg. For deep wounds,5-10-15 g of powder is applied to the wound cavity for external use. If there is no improvement after treatment or new symptoms appear, you should consult your doctor.

Overdose

Symptoms: nausea, vomiting, intestinal colic, dizziness, headache, drowsiness, depression, fainting, confusion, visual disturbances, fever, hematuria, crystalluria; with prolonged overdose – thrombocytopenia, leukopenia, megaloblastic anemia, jaundice. Treatment: heavy drinking; in case of accidental ingestion-gastric lavage.

Special instructions

During therapy, a plentiful alkaline drink is recommended. If necessary, simultaneously prescribe antimicrobial drugs inside. If hypersensitivity reactions occur, treatment should be discontinued. With long-term treatment, systematic monitoring of the blood picture, kidney and liver function is recommended.

Please read the instructions carefully before you start using the drug. Save the instructions, you may need them again.

If you have any questions, contact your doctor. The medicine you are being treated with is intended for you personally, and it should not be passed on to others, as it can cause harm to them even if you have the same symptoms as you do.

Influence on the ability to drive vehicles and mechanisms

Studies of the effect of the drug on the reaction rate when driving vehicles or working with other mechanisms have not been conducted. Taking into account the side effects of the drug (dizziness), care should be taken when driving vehicles and mechanisms.

Storage conditions

In a dark place at a temperature not exceeding 25 °C. Keep out of reach of children.

Shelf

life is 5 years.

Active ingredient

Sulfonamide

Description

For adults, For children

Indications

Wounds, Skin Infections, Bedsores, Burns, Boils, Pyoderma