Rengalin, pills for dissolution 20pcs

Product description

Rengalin is a drug for the treatment of productive and unproductive cough in adults and children from 3 years of age.

Composition

Composition (per 1 tablet): Active ingredients: Antibodies to bradykinin affinity purified-0.006 g * Antibodies to histamine affinity purified-0.006 g*Antibodies to morphine affinity purified-0.006 g*Excipients: isomalt 0.506 g, microcrystalline cellulose 0.0275 g, magnesium stearate 0.0055 g, citric acid anhydrous 0.005225 g, colloidal silicon dioxide 0.00275 g, sodium cyclamate 0.00275 g, sodium saccharin 0.000275 g. * are applied to isomalt as a mixture of three active water-alcohol dilutions of the substance, diluted respectively in 10012,10030,10050 times.

Pharmacological action

It has been experimentally shown that the components of the drug modify the activity of ligand-receptor interaction of endogenous regulators with the corresponding receptors: morphine antibodies – with opiate receptors; histamine antibodies – with H1-histamine receptors; bradykinin antibodies – with B1-bradykinin receptors; at the same time, the combined use of the components leads to an increased antitussive effect. In addition to antitussive action, the complex drug due to its components has anti-inflammatory, decongestant, anti-allergic, antispasmodic (antibodies to histamine, antibodies to bradykinin) and analgesic effect (antibodies to morphine). The complex drug Rengalin by modifying histamine-dependent activation of H1 receptors and bradykinin-dependent activation of B2 receptors selectively reduces the excitability of the cough center of the medulla oblongata, inhibits the central links of the cough reflex. Inhibiting the centers of pain sensitivity in the thalamus, it blocks the transmission of pain impulses to the cerebral cortex. It inhibits the flow of pain impulses from the periphery due to a decrease in the release of tissue and plasma algogens (histamine, bradykinin, prostaglandins, etc. ). Unlike narcotic analgesics, it does not cause respiratory depression, drug dependence, and does not have narcogenic and hypnotic effects. Relieves the symptoms of acute pharyngitis, laryngitis and bronchitis, reducing bronchospasm. Relieves systemic and local symptoms of allergic reactions by affecting the synthesis and release of histamine and bradykinin from mast cells.

Indications

Rengalin is indicated for use in adults and children over 3 years of age. Productive and unproductive cough in influenza and acute respiratory viral infections, acute pharyngitis, laryngotracheitis, acute obstructive laryngitis, chronic bronchitis and other infectious and inflammatory and allergic diseases of the upper and lower respiratory tract.

Use during pregnancy and lactation

The safety of using Rengalin in pregnant women and during breastfeeding has not been studied. If you need to take the drug, the benefit-risk ratio should be taken into account.

Contraindications

Children under 3 years of age. Increased individual sensitivity to the components of the drug. Hereditary fructose intolerance (due to the presence of maltitol in the composition).

Side effects

Possible reactions of increased individual sensitivity to the components of the drug.

Interaction

In the course of the conducted clinical studies, no data were obtained on the interaction of Rengalin with drugs used as concomitant therapy.

How to take, course of use and dosage

It is not intended to divide the tablet into parts. Inside. At one time – 1 tablet (keep in the mouth until completely dissolved). Apply 1-2 tablets 3 times a day outside of meals. Depending on the severity of the condition in the first three days, the frequency of admission can be increased to 4-6 times a day. The duration of therapy depends on the severity of the disease and is determined by the attending physician.

Overdose

In case of accidental overdose, dyspeptic phenomena (nausea, vomiting, diarrhea) are possible due to the excipients included in the preparation (maltitol, glycerol). Treatment-symptomatic

Description

Tablets are flat-cylindrical in shape, with a chamfer, with a risk on one flat side, with solid edges, from white to almost white in color. On the flat side with a risk, the inscription MATERIA MEDICA is applied, on the other flat side, the inscription RENGALIN is applied.

Form of production

Tablets for resorption. 10 tablets each in a contour cell pack made of polyvinyl chloride film and aluminum foil. 1,2 or 5 contour cell packages together with instructions for medical use are placed in a pack of cardboard.

Storage conditions

In a place protected from light, at a temperature not exceeding 25 °C. Keep out of reach of children.

Shelf

life is 3 years. Do not use after the expiration date.

Active ingredient

Antibodies

Dosage form

tablets for resorption

Description

For adults, Pregnant women as prescribed by a doctor, Nursing mothers as prescribed by a doctor, Children over 3 years of age

Indications

Laryngitis, Cold, Flu, Cough, Tracheitis, Bronchitis, Pharyngitis