Rennie, menthol pills, 24pcs

Composition

1 tablet contains:

Active ingredients:

calcium carbonate 680 mg;

magnesium carbonate basic 80 mg;

Auxiliary substances:

sucrose;

pre-gelatinized corn

starch; potato starch;

talc;

magnesium stearate;

light liquid paraffin;

flavoring agent.

Pharmacological action

Pharmaceutical group: antacid agent.

Pharmaceutical action:

Rennie is a topical antacid. It contains calcium carbonate and magnesium carbonate, which provide fast and long-lasting neutralization of excess hydrochloric acid in gastric juice, thereby exerting a protective effect on the gastric mucosa.

The achievement of the therapeutic effect within 3-5 minutes is due to the good solubility of the tablets and the high calcium content.

Pharmacokinetics:

 Suction

As a result of the interaction of Rennie® with gastric juice, soluble calcium and magnesium salts are formed in the stomach. the degree of absorption of calcium and magnesium from these compounds depends on the dose of the drug. The maximum absorption is 10% calcium and 15-20% magnesium.

Deduction

A small amount of absorbed calcium and magnesium is excreted by the kidneys. In the intestine, insoluble compounds are formed from soluble salts, which are excreted in the feces.

Pharmacokinetics in special clinical cases

With impaired renal function, the concentration of calcium and magnesium in plasma may increase.

Indications

Symptoms associated with increased acidity of gastric juice and reflux esophagitis (including those caused by errors in diet, medication, alcohol abuse, coffee, nicotine):

• heartburn;
• acid belching;
• periodic pain in the stomach;
• feeling of fullness or heaviness in the epigastric region;
• dyspepsia;
• dyspepsia of pregnant women.

Use during pregnancy and lactation

When used in the recommended doses, the drug does not pose a danger to the fetus or child.

Contraindications

• -severe renal failure;
• – hypercalcemia;
• – hypophosphatemia— – nephrocalcinosis—
• – children under 12 years of age;
• – hypersensitivity to the components of Rennie.

Side effects

If the recommended doses are observed, the drug is well tolerated, however, in very rare cases, allergic reactions are possible — rash, angioedema, anaphylactic reactions.

Interaction

Changes in the acidity of gastric juice during the use of antacids can lead to a decrease in the rate and degree of absorption of other drugs when taken simultaneously, so medications should be taken 1-2 hours before or after taking antacids.

Tetracycline antibiotics, fluoroquinolones, cardiac glycosides, levothyroxine, iron preparations, fluorides, phosphates-when used simultaneously, antacids reduce the absorption of these drugs.

Thiazide diuretics — when taken concomitantly with antacids, the concentration of calcium in the blood serum should be regularly monitored.

Anticholinergic drugs Drugs enhance and lengthen the action, slowing down the emptying of the stomach.

How to take, course of use and dosage

Inside, chew or hold in the mouth until completely absorbed.

Adults and children over 12 years of age (unless otherwise recommended by the doctor) if symptoms occur — 1-2 tablets. If necessary, you can repeat the drug after 2 hours.

The maximum daily dose is 11 tablets.

Overdose

Symptoms:  long-term use of the drug in high doses in patients with impaired renal function can cause hypermagnesemia, hypercalcemia, alkalosis, which are manifested by nausea, vomiting, muscle weakness.

Treatment:  you should cancel the drug and immediately consult a doctor.

Special instructions

When prescribing the drug to patients with impaired renal function, the concentration of magnesium, phosphorus and calcium in the blood serum should be regularly monitored.

Patients with impaired renal function are not recommended to take the drug for a long time in high doses.

High-dose use of Rennie® may increase the risk of kidney stones.

If the use of the drug is ineffective, you should consult a doctor for advice.

Form of production

Chewable tablets

Storage conditions

At a temperature not exceeding 25 °C.

Shelf life

3 years

Active ingredient

: Calcium Carbonate, Magnesium Carbonate

Dosage form

Tablets

Description

Nursing mothers, Pregnant women, Children over 12 years old, Adults

Indications

Gastritis, Reflux Esophagitis, Diet error, Gastric and Duodenal Ulcers, Flatulence, Heartburn