Rimantadine Avexima pills 50mg, 20pcs

Composition

Per tablet:

active ingredients:  

Rimantadine hydrochloride-50 mg;

excipients:  

lactose (milk sugar) – 60 mg,

potato starch-37 mg,

calcium stearate-1.5 mg,

talc-1.5 mg.

Indications

Prevention and early treatment of influenza A in adults and children over 7 years of age.

Contraindications

• Acute liver diseases,
• acute and chronic kidney diseases,
• thyrotoxicosis,
• hypersensitivity to rimantadine,
• pregnancy and lactation,
• children under 7 years of age,
• with lactase deficiency, lactose intolerance, lactose/isomaltose malabsorption syndrome (since the drug contains lactose).

Side effects

From the digestive system:  dry mouth, nausea, vomiting, loss of appetite, epigastric pain, flatulence;

central nervous system disorders:  headache, dizziness, insomnia, neurological reactions, impaired concentration, drowsiness, anxiety, increased excitability, fatigue;

other: hyperbilirubinemia, allergic reactions (skin rash, pruritus, urticaria).

Interaction

Rimantadine reduces the effectiveness of antiepileptic drugs. Paracetamol and ascorbic acid reduce the maximum concentration of rimantadine in blood plasma by 11%. Cimetidine reduces rimantadine clearance by 18%.

Adsorbents, binders and enveloping agents reduce the absorption of rimantadine. Urine alkalinizing agents (acetazolamide, sodium bicarbonate, etc. ) increase the effectiveness of rimantadine due to a decrease in its excretion by the kidneys.

How to take, course of use and dosage

Inside after a meal, washed down with water.

Flu treatment should be initiated within 24-48 hours after the onset of symptoms. Adults on the first day are prescribed 100 mg 3 times a day; on the second and third days,100 mg 2 times a day; on the fourth and fifth days,100 mg once a day. On the first day of the disease, it is possible to use the drug once in a dose of 300 mg.

Children aged 7 to 10 years are prescribed 50 mg 2 times a day; from 11 to 14 years-50 mg 3 times a day. Older than 14 years-adult doses. Take within 5 days. To prevent flu, adults are prescribed 50 mg once a day for up to 30 days. Children over 7 years of age – 50 mg once a day for up to 15 days.

Overdose

Symptoms: agitation, hallucinations, arrhythmia.

Treatment: gastric lavage, symptomatic therapy: measures to maintain vital functions.

Rimantadine is partially eliminated by hemodialysis.

Special instructions

When using rimantadine, it is possible to exacerbate chronic concomitant diseases. Elderly patients with arterial hypertension have an increased risk of hemorrhagic stroke.

If there is a history of epilepsy and ongoing anticonvulsant therapy with rimantadine, the risk of developing an epileptic seizure increases. In such cases, rimantadine is used at a dose of 100 mg per day simultaneously with anticonvulsant therapy.

In influenza caused by the B virus, rimantadine has an antitoxic effect. Preventive treatment is effective in contact with sick people, when the infection spreads in closed groups, and when there is a high risk of developing the disease during an influenza epidemic. Viruses that are resistant to the drug may appear.

During the treatment period, care should be taken when driving vehicles and engaging in other potentially dangerous activities that require increased concentration of attention and speed of psychomotor reactions.

Form of production

Tablets of white color, flat-cylindrical shape.

Storage conditions

 In a dark place, at a temperature not exceeding 25 °C.

Shelf life

5 years

Active ingredient

Rimantadine

Dosage form

Tablets

Indications

Prevention of flu, Tick-borne encephalitis, Influenza, SARS