Rinicold Broncho, syrup, 100ml

Composition

10 ml of syrup contains:

Active ingredients:  

ambroxol hydrochloride 15 mg;

chlorphenamine maleate 2 mg;

phenylephrine hydrochloride 5 mg;

guaifenesin 100 mg;

Auxiliary substances:

sucrose — 4000 mg;

methyl parahydroxybenzoate — 18 mg;

parahydroxybenzoate — 2 mg;

disodium edetate — 2 mg;

sorbitol 70% solution — 1000 mg;

glycerin (glycerol) 500 mg;

menthol 1 mg,

citric acid,2 mg;

sodium citrate 5 mg;

flavor melon — 0.03 ml;

dye “sunset” yellow (E 110) — 0,66 mg;

purified water — q. s. to 10 ml.

Pharmacological action

Rinicold Broncho-a combined drug, which includes guaifenesin and ambroxol, reduces the viscosity of bronchial secretions and facilitates expectoration. Chlorphenamine maleate has an anti-allergic effect: it eliminates lacrimation, itching in the eyes and nose. Phenylephrine hydrochloride has a vasoconstrictive effect, reduces swelling and hyperemia of the mucous membranes of the upper respiratory tract and paranasal sinuses.

Indications

Colds, flu and acute respiratory viral infections, accompanied by a cough with difficult-to-separate viscous sputum.

Contraindications

• seizures of different etiologies;
• severe atherosclerosis of the coronary arteries;
• arterial hypertension;
• diabetes mellitus;
• hyperthyroidism;
• pheochromocytoma;
• angle-closure glaucoma;
• ulcer disease of stomach and duodenum;
• benign prostatic hyperplasia;
• a deficiency of the enzyme glucose-6-phosphate dehydrogenase;
• pregnancy;
• lactation (breastfeeding);
• children age (to 6 years);
• concomitant use of tricyclic antidepressants, MAO inhibitors, beta-blockers;
• simultaneous reception of other medicines containing the Active ingredient, included in Ringold Broncho;
• hypersensitivity to the components of the drug.

Caution should be exercised in patients with renal and/or hepatic insufficiency.

Side effects

From the cardiovascular system:  possible rise in blood pressure, tachycardia.

From the central nervous system:  headache, drowsiness, dizziness, increased excitability, sleep disturbance. Children may experience agitation, restlessness, and irritability. In elderly patients, confusion and irritability are also possible.

From the digestive system:  nausea, vomiting, constipation, diarrhea, epigastric pain.

From the side of the visual organ:  mydriasis, paralysis of accommodation, increased intraocular pressure.

Allergic reactions:  skin rash, pruritus, angioedema.

Other services:  dryness of the mucous membranes, difficulty urinating.

Interaction

The drug enhances the effect of sedatives, ethanol.

Combined use with antidepressants, phenothiazine derivatives (chlorpromazine, trifluoperazine, levomepromazine), antiparkinsonian and antipsychotic agents increases the risk of urinary retention, dry mouth, constipation.

When used concomitantly with corticosteroids (prednisone, dexamethasone, triamcinolone), the risk of glaucoma increases. Chlorphenamine when used simultaneously with MAO inhibitors (nialamide), furazolidone can lead to a hypertensive crisis, agitation, hyperpyrexia.

Use together with tricyclic antidepressants increases the sympathomimetic effect, with halothane-increases the risk of ventricular arrhythmia, with guanethidine-reduces its hypotensive effect. Guanethidine, in turn, enhances the alpha-adrenostimulating activity of phenylephrine, which is part of the drug.

Simultaneous use of ambroxol and guaifenesin with antitussive agents leads to difficulty in sputum discharge.

How to take, course of use and dosage

Inside. Shake thoroughly before use!

The recommended dose for adults and children over 12 years of age is 20 ml (4 teaspoons) 3 times a day. The recommended dose for children 6-12 years is 10 ml (2 teaspoons) 2-3 times a day. Taking the drug should be evenly distributed throughout the day.

Overdose

Symptoms:  increased severity of side effects.

Treatment:  gastric lavage, taking activated charcoal, laxatives (vaseline oil, saline laxatives); symptomatic therapy. In case of severe violations, you should consult a doctor.

Special instructions

It is not recommended to take the drug for more than 7 days without a doctor’s appointment.

When using the drug, urine may turn pink.

Form of production

Syrup

Storage conditions

At a temperature not exceeding 25 °C (do not freeze).

Shelf life

3 years

Active ingredient

Ambroxol, Guaifenesin, Phenylephrine, Chlorphenamine

Dosage form

oral solution