Sanofi Troxerutin capsules 300mg, 90pcs

Composition

1 capsule contains:

Active ingredient:  

troxerutin 300 mg;

excipients:

macrogol 6000 12.00 mg,

magnesium stearate 3.12 mg;

capsule shell:

body – titanium dioxide 2%, gelatin up to 100%; lid – dye quinoline yellow 0.713%, dye iron oxide red 0.005%, titanium dioxide 2,000%, gelatin up to 100%.

Pharmacological action

Semisynthetic bioflavonoid (rutin derivative) of the benzopyrane class. Venotonizing, angiprotective agent. Reduces the permeability and fragility of capillaries, strengthens the vascular wall, improves microcirculation, and has an anti-edematous effect.

Participates in redox processes, has antioxidant activity. Increases the density of the vascular wall, reduces the exudation of the liquid part of the blood plasma and diapedesis of blood cells in the tissue, reduces inflammation in the vascular wall, limiting the adhesion of platelets to its surface.

The use of troxerutin is possible both at the initial and late stages of treatment of chronic venous insufficiency, it can be used as one of the components of complex treatment.

Troxerutin reduces swelling and heaviness in the legs, reduces the intensity of pain and cramps, and improves tissue trophism.

Troxerutin relieves the symptoms associated with hemorrhoids (pain, exudation, itching, bleeding).

Troxerutin helps slow the progression of diabetic retinopathy due to its effect on the permeability and resistance of capillary walls.

The effect of troxerutin on the rheological properties of blood helps prevent the development of retinal vascular microthrombosis.

Indications

-chronic venous insufficiency;

– trophic disorders in chronic venous insufficiency (dermatitis, trophic ulcers);

– varicose veins;

– superficial thrombophlebitis, periflebitis;

– post-thrombotic syndrome;

– post-traumatic edema, hematomas;

– hemorrhoids;

– diabetic angiopathy, retinopathy.

Contraindications

-hypersensitivity to troxerutin and other components of the drug;

– peptic ulcer of the stomach and duodenum;

– chronic gastritis (in the acute phase);

– pregnancy (I trimester);

– breastfeeding;

– children under 18 years of age (limited experience).

With caution:

In patients with chronic renal failure (long-term use).

Side effects

Troxerutin is very well tolerated, with mild adverse reactions occurring in rare cases.

Immune system disorders:  hypersensitivity reactions.

Nervous system disorders:  headache.

Gastrointestinal disorders: irritation of the gastrointestinal mucosa, nausea.

Skin and subcutaneous tissue disorders:  skin rashes, itching.

Vascular disorders:  “flushes” of blood to the face.

Interaction

Ascorbic acid

When used simultaneously, it enhances the effect of ascorbic acid on resistance and permeability of the vascular wall.

How to take, course of use and dosage

Inside. Capsules should be swallowed whole, with a meal, with a sufficient amount of liquid.

The drug troxerutin is used as prescribed by a doctor.

Usually prescribed 1 capsule inside 3 times a day; as maintenance therapy-1 capsule 2 times a day.

The course of treatment is on average 3-4 weeks, the need for longer treatment is determined individually.

Overdose

Troxerutin has very low toxicity.

Symptoms of overdose: agitation, nausea, headache and “hot flashes” of blood to the face.

In case of overdose, patients should wash their stomach, take activated charcoal (within an hour after taking it), consult a doctor, and if necessary, conduct symptomatic and supportive treatment.

Special instructions

Experience with the use of troxerutin in children under the age of 18 years is insufficient.

In the treatment of superficial thrombophlebitis or deep vein thrombosis, the use of troxerutin does not exclude the need for anti-inflammatory and antithrombotic therapy.

Influence on the ability to drive vehicles and mechanisms:

Taking troxerutin does not affect motor and mental reactions, does not interfere with driving vehicles and working with mechanisms.

Storage conditions

At a temperature not exceeding 25 °C.

Keep out of reach of children.

Shelf

life is 3 years.

Do not use after the expiration date.

Active ingredient

Troxerutin

Dosage form

Capsules

Description

For adults, Pregnant women in the second and third trimester as prescribed by a doctor

Indications

Dermatitis, Thrombophlebitis, Vascular lesions in diabetes mellitus, Edema after injuries and operations, Hemorrhoids, Varicose veins, Trophic ulcers