Composition
Active ingredient:
heptapeptide 10 mg.
Auxiliary substance:
nipagin 1 mg (preservative).
Pharmacological action
Semax 1% — “First aid” for stroke. Thanks to its Form of production – drops in the nose – it instantly begins to act, preserving nerve cells from damage and minimizing the consequences of an acute violation of the blood supply to the brain. Prevents the occurrence of repeated strokes. Relieves post-stroke depression.
Pharmacokinetics
It is absorbed from the nasal mucosa, while it is absorbed up to 60-70% in terms of the Active ingredient. Semax is rapidly distributed to all organs and tissues, penetrates through the blood-brain barrier.
Indications
for recovery from stroke; acute period of ischemic stroke; transient ischemic attacks;acute period of TBI.
Use during pregnancy and lactation
Contraindicated
Contraindications
pregnancy, breast-feeding; hypersensitivity to the components of the drug; acute psychotic states, disorders accompanied by anxiety;diseases of the endocrine system.
Side effects
With prolonged use: possible-mild irritation of the nasal mucosa.
Interaction
Given the method of use of Semax (intranasal), it is undesirable to introduce drugs that have a local vasoconstrictive effect when administered intranasally.
How to take, course of use and dosage
Semax is applied intranasally.
As an emergency medical aid in the first minutes and hours of stroke occurrence – at the prehospital stage – “Semax 1%” is administered 3 drops in each nasal passage every 20 minutes before admission to the hospital.
At the stage of treatment in the hospital, “Semax 1%” is used:
Moderate stroke – 3 drops in each nasal passage 4 times a day for 10 days.
Severe stroke – 3 drops in each nasal passage 6 times a day for 10 days.
Transient ischemic attacks (TIA) treatment at the hospital stage – 3 drops in each nasal passage 3-6 times a day for 10 days.
Overdose
The information is not described.
Special instructions
Do not use after the expiration date indicated on the product packaging.
Form of production
Drops in the nose
Storage conditions
In a dark place at a temperature not exceeding +10°C. Keep out of reach of children.
Shelf
life is 2 years.
Active ingredient
Methionyl-glutamyl-histidyl-phenylalanyl-prolyl-glycyl-proline
Conditions of release from pharmacies
By prescription
Dosage form
nasal drops
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Side effects of Semax, nasal drops 1%, 3ml
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