Indications
Hypo-and avitaminosis C; increased need for ascorbic acid (period of intensive growth, pregnancy, lactation, increased physical activity, period of convalescence).
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Active ingredient: |
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Hypo-and avitaminosis C; increased need for ascorbic acid (period of intensive growth, pregnancy, lactation, increased physical activity, period of convalescence).
With caution
Diabetes mellitus, glucose-6-phosphate dehydrogenase deficiency; for use in large doses-hemochromatosis, sideroblastic anemia, thalassemia, hyperoxaluria, nephrourolithiasis.
Active ingredients:
ascorbic acid 100 mg;
dextrose 877 mg.
Minimum order quantity-5 pieces
Active ingredients:
ascorbic acid 100 mg;
dextrose 877 mg
Pharmacotherapeutic group: vitamin.
ATX code: A 11GB.
Pharmacological properties
Pharmacodynamics
Ascorbic acid plays an important role in the regulation of redox processes, carbohydrate metabolism, blood clotting, tissue regeneration, and increases the body’s resistance. Ascorbic acid (vitamin C) is not formed in the human body, but comes only from food. With a balanced and full-fledged diet, a person does not experience a deficiency in vitamin C.
Dextrose is involved in various metabolic processes in the body, enhances redox processes in the body, improves the antitoxic function of the liver.
Pharmacokinetics
It is completely absorbed by the body, not excreted by the kidneys (the appearance in the urine is a pathological sign).
Hypo-and avitaminosis C; increased need for ascorbic acid (period of intensive growth, pregnancy, lactation, increased physical activity, period of convalescence).
With caution
Diabetes mellitus, glucose-6-phosphate dehydrogenase deficiency; for use in large doses-hemochromatosis, sideroblastic anemia, thalassemia, hyperoxaluria, nephrourolithiasis.
Allergic reactions, irritation of the gastrointestinal mucosa (nausea, vomiting, diarrhea, spasm of the gastrointestinal tract); suppression of the function of the insular apparatus of the pancreas (hyperglycemia, glucosuria); when used in high doses – hyperoxaluria and nephrocalcinosis (oxalate).
Changing laboratory parameters: thrombocytosis, hyperprothrombinemia, erythropenia, neutrophilic leukocytosis, hypokalemia.
Ascorbic acid increases the concentration of benzylpenicillin and tetracyclines in the blood; at a dose of 1 g / day. increases the bioavailability of ethinyl estradiol (including that included in oral contraceptives).
Improves intestinal absorption of iron preparations (converts trivalent iron to bivalent); may increase iron excretion when used concomitantly with deferoxamine.
Reduces the effectiveness of heparin and indirect anticoagulants.
The drug is taken orally, after a meal. It can be ground before use.
For preventive purposes, prescribe: – adults-50-100 mg / day; – children from 6 to 14 years-50 mg / day, children from 14 to 18 years-75 mg / day; – during pregnancy and lactation-300 mg / day for 10-15 days, then 100 mg/day.
For therapeutic purposes, prescribe: – adults – 50-100 mg 3-5 times a day; – children – 50-100 mg 2-3 times a day.
The maximum daily dose for adults is 1000 mg, for children-500 mg. The duration of treatment depends on the nature and course of the disease and is recommended by the doctor.
Symptoms: when using more than 1 g – headache, increased excitability of the central nervous system, insomnia, nausea, vomiting, diarrhea, hyperacid gastritis, ulceration of the gastrointestinal mucosa, suppression of the function of the insular pancreatic apparatus (hyperglycemia, glucosuria), hyperoxaluria, nephrolithiasis (from calcium oxalate), damage to the glomerular apparatus of the kidneys, moderate pollakiuria (when taking a dose of more than 600 mg/day. ).
Reduced capillary permeability (possible deterioration of tissue trophism, increased blood pressure, hypercoagulation, development of microangiopathies.
Due to the stimulating effect of ascorbic acid on the synthesis of corticosteroid hormones, it is necessary to monitor kidney function and blood pressure.
With prolonged use of large doses, the function of the pancreatic insular apparatus may be inhibited, so it should be regularly monitored during treatment.
In patients with high iron content in the body, ascorbic acid should be used in minimal doses. Prescribing ascorbic acid to patients with rapidly proliferating and intensely metastatic tumors may worsen the course of the process.
Ascorbic acid as a reducing agent can distort the results of various laboratory tests (blood glucose, bilirubin, liver transaminase activity, and LDH).
Tablets
B at a temperature of 15° to 25°C.
life is 1 year. Do not use after the expiration date indicated on the package.
Ascorbic Acid, Dextrose
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