Chlosol, bottles, 200ml

Composition

1 l:  – sodium acetic acid trihydrate (in terms of anhydrous salt) 3.6 g-sodium chloride 4.75 g-potassium chloride 1.5 g water for injection up to 1 liter

Pharmacological action

Pharmaceutical group:

rehydrating agent.

Pharmaceutical action:

Chlosol is a combined saline solution for rehydration and detoxification. It has a hemodynamic effect, reducing hypovolemia (a decrease in the volume of circulating blood), preventing blood clot and the development of metabolic acidosis (acidification with metabolic disorders, vomiting, heavy sweating, etc. ); improves capillary (through the smallest vessels) blood circulation, the functional ability of the heart and kidneys; increases diuresis and has a detoxifying effect.

Pharmacokinetics:  

The drug is not long in the vascular bed (contains crystalloids with a low molecular weight, easily penetrates through the walls of capillaries), quickly passes into the interstitial space. It is excreted by the kidneys, increasing diuresis (removes harmful substances from the body).

Indications

Rehydration, intoxication on the background of dehydration (including cholera, acute dysentery, food toxicoinfection).

Contraindications

-hypersensitivity to the components of the drug Chlosol-hyperkalemia-alkalosis – renal failure – heart failure

Side effects

-edema-tachycardia-hyperkalemia occasionally: chills.

Interaction

It is not recommended to prescribe a solution of Chlosol with potassium preparations and potassium-sparing diuretics.

How to take, course of use and dosage

Intravenous jet or drip.

Within 1 hour, the solution is administered in an amount corresponding to 7-10% of the patient’s body weight, then the jet injection is replaced with a drip, for 24-48 hours at a rate of 40-120 drops/min.

Before use, the solution is heated to body temperature.

The solution is administered in the amounts necessary to restore the volume of lost fluid. The balance of injected and lost fluids is determined every 6 hours.

Special instructions

Therapy is carried out under the control of hematocrit and blood electrolyte concentration. With the development of hyperkalemia, the solution can be replaced with a solution of Disol until the electrolyte balance is normalized.

Its use in pediatric practice is not described.

Features of the drug’s effect on the ability to drive a vehicle or potentially dangerous mechanisms:

It doesn’t affect you.

Storage conditions

In a dry place, at a temperature not exceeding 25 °C

Shelf life

2 years

Active ingredient

Potassium Chloride, Sodium Acetate, Sodium Chloride

Conditions of release from pharmacies

By prescription

Dosage form

infusion solution