Derinat, spray 0.25% 10ml

Composition

1 ml of the solution contains sodium deoxyribonucleate-2.5 mg,

sodium chloride-1.0 mg

Pharmacological action

The drug activates cellular and humoral immunity. Optimizes specific responses against fungal, viral and bacterial infections. The drug stimulates reparative and regenerative processes, normalizes the condition of tissues and organs in dystrophies of vascular origin.

Derinat promotes the healing of trophic ulcers of various etiologies. Derinat promotes rapid healing of deep burns, significantly accelerating the dynamics of epithelialization. When restoring ulcerative formations on the mucosa under the action of Derinat, scar-free recovery occurs. The drug does not have teratogenic and carcinogenic effects.

Pharmacokinetics:

Derinat when applied topically is rapidly absorbed and distributed in organs and tissues with the participation of the endolymphatic transport pathway. In the phase of intensive intake of the drug into the blood, redistribution occurs between plasma and shaped blood elements, in parallel with metabolism and excretion. Derinate is metabolized in the body.

It is excreted from the body (in the form of metabolites) partly in the faeces, and, to a greater extent, in the urine according to a biexponential dependence.

Indications

Monotherapy:

• acute respiratory diseases (ARI);
• prevention and treatment of acute respiratory viral infections (ARVI);
• ophthalmology: inflammatory and dystrophic processes;
• inflammatory diseases of the oral mucosa;

Complex therapy:

• chronic inflammatory diseases, fungal, bacterial and other infections of the mucous membranes in gynecology;
• acute and chronic diseases of the upper respiratory tract (rhinitis, sinusitis, sinusitis, sinusitis);
• obliterating diseases of the lower extremities,
• trophic ulcers, long-unhealed and infected wounds (including diabetes mellitus);
• gangrene;
• burns, frostbite;
• hemorrhoids;
• postradiation necrosis of the skin and mucous membranes.

Contraindications

• hypersensitivity to the components of the drug.

Side effects

No side effects were detected with external or topical application of the drug.

How to take, course of use and dosage

Derinat in the form of a solution for external and topical use is prescribed depending on the localization of the pathological process. The drug is prescribed to children from the first day of life and adults. For the prevention of acute respiratory viral infections,2 drops are instilled into each nasal passage 2-4 times a day for 1-2 weeks.

When symptoms of a respiratory disease appear, the drug is instilled 2-3 drops in each nasal passage every 1-1.5 hours during the first day, then 2-3 drops in each nasal passage. The duration of the course of therapy is from 5 days to 1 month. For inflammatory diseases of the nasal cavity and paranasal sinuses, the drug is instilled 3-5 drops in each nasal passage 4-6 times a day; the course duration is 7-15 days. In case of inflammatory diseases of the oral cavity, the oral cavity is rinsed with a solution of the drug 4-6 times a day (1 bottle for 2-3 rinses). The duration of the course of therapy is 5-10 days.

For chronic inflammatory diseases, fungal, bacterial and other infections in gynecological practice-intravaginal injection of tampons with the drug or irrigation of the vagina and cervix at 5 ml per procedure 1-2 times a day for 10-14 days. For hemorrhoids, the drug is administered rectally with microclysters of 15-40 ml.

The duration of treatment is 4-10 days. In ophthalmological practice, in severe inflammatory and dystrophic processes, Derinat is instilled into the eyes 1-2 drops 2-3 times a day for 14-45 days. In case of obliterating diseases of the lower extremities, in order to achieve a systemic effect, the drug is instilled 1-2 drops in each nasal passage 6 times a day, the course duration is up to 6 months.

With post-radiation necrosis of the skin and mucous membranes, with long-term non-healing wounds, burns, frostbite, trophic ulcers of various etiologies, gangrene on the affected areas, it is recommended to apply application dressings (gauze in 2 layers) with the application of the drug 3-4 times a day or treat the affected surface with a spray of 10-40 ml 4-5 times a day. The course of treatment is 1-3 months.

Form of production

Spray.

Storage conditions

The drug is recommended to be stored in a dry place protected from light at a temperature of 4° to 18°C.

Active ingredient

Sodium Deoxyribonucleate

Dosage form

nasal spray

Description

Nursing Mothers, For children, For pregnant women, For Adults

Indications

Female Genital inflammation, Bedsores, Colds, Sinusitis, Flu and cold prevention, Flu, Frostbite, Hemorrhoids, Burns, Sinusitis, Trophic Ulcers, Runny Nose