Diosmin pills 600mg, 30pcs – Izvarino

Composition

1 film-coated tablet contains: Composition of the tablet core: Active ingredient: diosmin – 600.0 mg. Excipients: microcrystalline cellulose, povidone K 30, colloidal silicon dioxide, magnesium stearate. Composition of the tablet shell 1: opadray II pink (85F34610) (polyvinyl alcohol, titanium dioxide, macrogol 3350, talc, iron oxide yellow dye, iron oxide red dye, iron oxide black dye). Composition of the tablet shell 2: shellac.

Pharmacological action

Venotonizing effect: reduces the extensibility of the veins, increases venous tone, reduces venous congestion, increases the vasoconstrictive effect of epinephrine, norepinephrine. One tablet contains 600 mg of diosmin, which is the optimal effective daily dose for venotonizing action. Angioprotective effect: improves microcirculation, increases capillary resistance, reduces their permeability. Effect on the lymphatic system: improves lymphatic drainage, increases the tone and frequency of contraction of lymphatic capillaries, increases their functional density, reduces lymphatic pressure. It has a decongestant effect. Reduces the symptoms of inflammation (dose-dependent effect). Reduces the adhesion of leukocytes to the venous wall and their migration to paravasal tissues; improves oxygen diffusion and perfusion in the tissues. Blocks the production of free radicals, prostaglandins and thromboxane synthesis. Clinical studies have confirmed: a decrease in mean venous pressure in the system of superficial and deep veins of the lower extremities, demonstrated in a double-blind placebo-controlled study conducted under the control of Dopplerography, as well as an increase in systolic and diastolic blood pressure in patients with postoperative orthostatic hypotension.

Indications

Treatment of symptoms of lymphovenous insufficiency of the lower extremities (feeling of heaviness, fatigue, bursting in the legs, pain that increases by the end of the day, swelling). Treatment of acute hemorrhoid symptoms. Additional treatment for microcirculation disorders.

Contraindications

Hypersensitivity to the components of the drug, children under 18 years of age (limited experience), not recommended during breastfeeding (limited experience).

Side effects

The frequency of adverse reactions is presented as follows: very common (≥ 1/10), common (≥ 1/100, < 1/10), uncommon (≥ 1/1000, < 1/100), rare (≥ 1/10000, < 1/1000), very rare ( From the gastrointestinal tract: rarely-dyspeptic disorders (heartburn, nausea, abdominal pain). From the central nervous system: rarely-headache. If any of the side effects listed in the instructions get worse or you notice any other side effects not listed in the instructions, tell your doctor.

Interaction

Clinically significant interaction effects with other drugs have not been described. You should inform your healthcare provider about all medications you are taking.

How to take, course of use and dosage

The drug is intended for oral use. Lymphovenous insufficiency outside the lower extremities In case of chronic lymphovenous insufficiency,1 tablet is prescribed per day in the morning, preferably before meals. Usually, the course of taking the drug is 2 months. Acute hemorrhoids and exacerbation of chronic hemorrhoids In acute hemorrhoids and exacerbation of chronic hemorrhoids, the drug is prescribed in the first four days 1 tablet 3 times a day with meals, in the next three days 1 tablet 2 times a day with meals. If symptoms recur, the course of treatment may be repeated on the doctor’s recommendation. Chronic hemorrhoids After stopping acute events, it is recommended to continue taking the drug 1 tablet 1 time a day for 1-2 months. If one or more doses of the drug are missed, it is necessary to continue using Diosmin in the usual mode and in the usual dose. Before using the drug, you should consult your doctor

Special instructions

Treatment of an acute attack of hemorrhoids is carried out in combination with other drugs, in the absence of a rapid clinical effect, it is necessary to conduct an additional examination and adjust the therapy. In cases of venous circulatory disorders (varicose veins of the lower extremities, chronic lymphovenous insufficiency of the lower extremities), the maximum effect of treatment is provided by combining therapy with lifestyle changes: it is advisable to avoid prolonged stay in an upright position, reduce excess body weight. In some cases, the wearing of special stockings (compression knitwear) helps to improve blood circulation. If there is no reduction or if the symptoms of the disease become more severe, consult your doctor! Do not exceed the maximum time and recommended doses of the drug without consulting your doctor! 

Storage conditions

In a dark place at a temperature not exceeding 25 °C. Keep out of reach of children.

Shelf

life is 3 years. Do not use after the expiration date.

Active ingredient

Diosmin

Dosage form

Tablets

Description

For adults as prescribed by a doctor, for pregnant women as prescribed by a doctor

Indications

Trophic Ulcers, Varicose veins, Hemorrhoids, Vascular eye diseases