Dolgit gel 5%, 50g

Composition

100 g of gel contains 5 g of the Active ingredient ibuprofen;

excipients:

isopropanol,

dimethylhydroxymethyldioxolan (Solketal),

poloxamer a; b; c = 101; 56; 101 (Poloxamer 407, Pluronic F 127),

medium-chain triglycerides (Migliol 812),

purified water,

lavender oil,

orange blossom oil (nerol oil).

Pharmacological action

The drug has a local analgesic and anti-inflammatory effect. Suppresses the production of inflammatory mediators. It selectively blocks cyclooxygenase (COX-1 and COX-2) and has an inhibitory effect on the synthesis of prostaglandin, prostacyclin and thromboxane.

The analgesic effect is most pronounced in inflammatory pain: the drug weakens the pain syndrome with pain at rest and during movement; reduces morning stiffness and swelling of the joints; helps to increase the volume of movement. In addition to the anti-inflammatory effect, ibuprofen reduces platelet aggregation at the site of inflammation, as well as white blood cell migration and the release of lysosomal enzymes in the area of inflammation.

When the gel is applied to the skin, ibuprofen penetrates deeper tissues (subcutaneous tissue, muscles, joints, synovial fluid) and reaches therapeutic concentrations in them. The therapeutic effect in the application area is achieved by direct distribution through the skin into the target tissue. In a small amount is determined in the blood plasma. With the recommended method of application, the concentration in the synovial fluid is about 2 micrograms/ml.

Indications

• Inflammatory and degenerative diseases of the musculoskeletal system:
• Arthritis (rheumatoid, psoriatic).
• Joint syndrome in rheumatism and gout exacerbation.
• Shoulder-scapular periarthritis.
• Ankylosing spondylitis (ankylosing spondylitis).
• Deforming osteoarthritis.
• Osteochondrosis with radicular syndrome.
• Sciatica.
• Sciatica.
• Myalgia (rheumatic and non-rheumatic origin).
• Lumbago.
• Tendivitis, tendovaginitis, bursitis.
• Injuries (sports, industrial, domestic) without violating the integrity of soft tissues (including dislocations, sprains, muscle or ligament tears, bruises, post-traumatic soft tissue edema).

Use during pregnancy and lactation

It is contraindicated to use the drug during pregnancy and lactation.

Contraindications

Hypersensitivity to ibuprofen, components of the drug and other NSAIDs; bronchial asthma, urticaria, rhinitis caused by taking acetylsalicylic acid; wet dermatoses, eczema, violations of the integrity of the skin at the site of application of the gel, including infected wounds and abrasions; pregnancy (III trimester), children under 12 years of age.

Side effects

The drug is usually well tolerated. In rare cases, there may be temporary signs of local skin irritation in the form of redness, swelling, rashes, itchy skin, burning and tingling sensations. In case of hypersensitivity to NSAIDs, bronchospasm may occur. Long-term use of the drug in particularly sensitive patients may lead to the development of systemic side effects, which should stop taking the drug and consult a doctor.

Interaction

Drug interactions with other drugs are not described.

However, it should be borne in mind that even when applied topically, ibuprofen has a systemic effect, and, theoretically, when the gel is used simultaneously with other NSAIDs, side effects may increase.

How to take, course of use and dosage

EXTERNALLY! A strip of gel 5-10 cm long is applied to the area of damage and thoroughly rubbed with light movements until completely absorbed 3-4 times a day. The duration of treatment depends on the severity of the disease and the nature of the damage, and is, on average,2-3 weeks.

Overdose

Cases of overdose of the drug are not described.

In case of accidental ingestion of the drug, it is necessary to stimulate vomiting, gastric lavage, and take activated charcoal. Further treatment, if necessary, is symptomatic.

Special instructions

In severe cases, it is recommended to combine the gel externally with the use of other medicinal forms of NSAIDs (parenterally, orally, rectally).

Avoid contact with the gel in the eyes and on the mucous membranes.

The use of the drug does not affect activities that require increased attention, coordination of movements, high speed of mental and physical reactions (for example, in transport drivers, people working with complex mechanisms, etc. ).

Form of production

Gel for external use 5%.20 g,50 g of gel in an aluminum tube with an internal protective varnish coating, sealed with a membrane and a screw-on plastic cap.

One tube together with the instructions for use is placed in a cardboard box.

Storage conditions

Store in a dry place, at a temperature of 15-25 °C.

Keep out of the reach of children!

Shelf

life is 2.5 years.

Active ingredient

Ibuprofen

Dosage form

gel for external use

Description

Children over 1 year old, For adults

Indications

Osteoarthritis, Arthritis, Osteoarthritis, Lumbago, Rheumatoid Arthritis, Swelling after injuries and operations, Periarthritis, Sciatica