Evkazolin Aqua, spray 0.1%, 10ml

Composition

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of 1 g of nasal spray contains:

Active ingredient:

xylometazoline hydrochloride (in terms of 100% substance) 1 mg;

Auxiliary substances:

benzalkonium chloride (in terms of 100% substance) — 0.15 mg,

eucalyptus oil — 1 mg,

disodium edetate dihydrate — 0.15 mg;

propylene glycol — 60 mg;

macrogol 1500 — 50 mg;

povidone (15) — 7.5 mg;

hypromellose (5) — 0.5 mg;

Polysorbate 20 (tween-20) — 10 mg;

sodium hydrogen phosphate dodecahydrate — 0.5 mg;

potassium dihydrogen phosphate 1 mg;

water for injection — up to 1 g

of Pharmacological action

Vasoconstrictor for topical use in ENT practice. Alpha-adrenomimetic.

When applied to the mucous membranes, it causes vasoconstriction, which reduces local hyperemia and edema.

With rhinitis, it facilitates nasal breathing.

Pharmacokinetics

When applied topically, it is practically not absorbed, and plasma concentrations are so low that they cannot be determined by modern analytical methods.

Indications

Acute allergic rhinitis, sinusitis, pollinosis, otitis media (to reduce swelling of the nasopharyngeal mucosa), preparation of the patient for diagnostic procedures in the nasal passages.

Contraindications

Angle-closure glaucoma, atrophic rhinitis, arterial hypertension, tachycardia, severe atherosclerosis, hyperthyroidism, surgical interventions on the meninges (in the anamnesis), hypersensitivity to xylometazoline.

Side effects

With frequent and/or prolonged use — irritation and / or dryness of the nasopharyngeal mucosa, burning and paresthesia of the nasal mucosa, sneezing, hypersecretion of the nasal mucosa; swelling of the nasal mucosa, palpitation, tachycardia, arrhythmias, increased blood pressure, headache, vomiting, insomnia, visual impairment; depression.

Interaction

Xylometazoline interacts with other drugs only when a resorptive effect is shown.

Other adrenomimetics may enhance the effect of xylometazoline.

Adrenoblockers and sympatholytics, BCC weaken its effect.

The drug enhances the hypertensive effect of tricyclic antidepressants and MAO inhibitors.

How to take, course of use and dosage

Intranasally. Adults and children over 6 years of age — 1 injection in each nasal passage 3-4 times a day. The course of treatment depends on the course of the disease and should not exceed 5-7 consecutive days.

After the end of the course of treatment, the drug can be prescribed again only after a few days.

Overdose

Symptoms: decreased body temperature, bradycardia, increased blood pressure.

Treatment: symptomatic.

Special instructions

The drug Eucazoline Aqua should not be used continuously for long periods (more than 7 consecutive days).

Do not exceed the recommended dose of the drug, especially in the treatment of children and the elderly.

Use with caution when driving vehicles or performing other types of work that require increased concentration of attention and rapid psychomotor reactions.

Form of production

Spray for nasal use

Storage conditions

In a dark place, at a temperature not exceeding 25 °C.

Shelf

life is 2 years.

Active ingredient

Xylometazoline

Dosage form

nasal spray

Description

For adults, Children over 6 years of age, Nursing mothers as prescribed by a doctor

Indications

Cold, Sinusitis, Pollinosis, Flu, Allergy, Allergic Rhinitis, Sinusitis, Runny Nose, Otitis