Folic acid pills 50pcs

Product description

dietary supplements. It is not a medicinal product

Composition

1 tablet contains folic acid 1 mg

Pharmacological action

Replenishes folic acid deficiency, stimulates erythropoiesis.

Folic acid – folacin, water-soluble folate, vitamin B9. In the body, it is converted to tetrahydrofolic acid, which is necessary for the maturation of megaloblasts and their transformation into normoblasts.

When it is deficient, a megaloblastic type of hematopoiesis develops. It plays an important role in the exchange of purines and pyrimidines, the synthesis of nucleic acids, and the metabolism of amino acids (glycine, methionine, and histidine).

After oral use, folic acid combines with the internal Castle factor (a specific glycoprotein) in the stomach and is absorbed in the upper duodenum.

It binds almost completely to plasma proteins.

It is activated in the liver under the influence of the enzyme dihydrofolate reductase, turning into tetrahydrofolic acid. Cmax in the blood is reached in 30-60 minutes.

It is excreted by the kidneys both in unchanged form and in the form of metabolites.

Indications

Megaloblastic anemia, spru, drug and radiation anemia and leukopenia, post-resection anemia, chronic gastroenteritis, intestinal tuberculosis, folic acid deficiency.

Prevention of folic acid deficiency in the body (including during pregnancy and lactation).

Contraindications

Hypersensitivity to folic acid.

Folic acid can be used during pregnancy and lactation in the recommended doses.

Side effects

Allergic reactions: bronchospasm, erythema, fever, skin rashes.

Interaction

When used concomitantly with chloramphenicol, neomycin, polymyxins, tetracyclines, folic acid absorption decreases.

When used concomitantly, folic acid reduces the effects of phenytoin, primidone, PASC, sulfasalazine, oral hormonal contraceptives, and chloramphenicol.

Folic acid increases the metabolism of phenytoin.

How to take, course of use and dosage

For therapeutic purposes, adults – 5 mg / day; children – in smaller doses, depending on age. The course of treatment is 20-30 days. To prevent folic acid deficiency in the body, it is used in doses of 20-50 mcg/day.

The daily requirement for folic acid is for children 1-6 months-25 mcg,6-12 months-35 mcg,1-3 years-50 mcg,4-6 years-75 mcg,7-10 years-100 mcg,11-14 years-150 mcg,15 years and older-200 mcg.

During pregnancy-400 mcg/day, during lactation-300 mcg/day.

Special instructions

In pernicious anemia, folic acid should only be used together with cyanocobalamin, since folic acid, while stimulating hematopoiesis, does not prevent the development of neurological complications (including funicular myelosis).

Long-term use of folic acid (especially in high doses) is not recommended because of the risk of a decrease in the concentration of cyanocobalamin in the blood.

Storage conditions

Store in a dry place, protected from light, at a temperature not exceeding 25 °C

Active ingredient

Folic acid

Conditions of release from pharmacies

Without a prescription

Dosage form

Tablets

Description

For adults

Indications

Hypovitaminosis, Malnutrition, Anemia