Fucidin, cream 2%, 15g

Composition

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of 1 g of cream for external use contains:

Active ingredient:

fusidic acid hemihydrate (in terms of anhydrous acid)  20.4 mg (equivalent to 20 mg of anhydrous fusidic acid),

Auxiliary substances:

cetyl alcohol — 111 mg;

glycerol 85% — 111 mg;

paraffin liquid (contains about 10 ppm alpha-tocopherol) — 111 mg;

paraffin soft white (contains about 10 ppm alpha-tocopherol) — 56 mg;

Polysorbate 60 — 56 mg;

hydrochloric acid q. s. to pH 5;

potassium sorbate — 2.7 mg;

butylhydroxyanisole — 0.04 mg;

water for about 531 mg

Pharmacological action

Futsidin has an antibacterial effect.

Fusidic acid belongs to the group of fusidins, antimicrobial compounds whose mechanism of action is associated with a violation of protein synthesis in the bacterial cell.

Fusidic acid is susceptible to gram-positive bacteria and gram-negative cocci, such as Staphylococcus aureus, Staphylococcus epidermidis (including methicillin-resistant strains), Nocardia asteroides, Corynebacterium minutissimum, Streptococcus pyogenes, Pseudomonas spp., Clostridium spp., Neisseria meningitidis, Neisseria gonorrhoeae.

It is inactive against Escherichia coli, Salmonella spp., Proteus spp. and other gram-negative bacteria, as well as protozoa and fungi.

Pharmacokinetics

The permeability of fusidic acid through intact skin is low. It does not enter the systemic circulation.

Indications

Skin infections caused by bacteria sensitive to fusidic acid.

Contraindications

Hypersensitivity to the components of the drug Fucidin.

With caution: pregnancy, lactation.

Side effects

Side effects are very rare and can be expected in about 5% of patients.

Determination of the frequency of adverse reactions: very common (> 1/10), common (>>1/100 and >>< 1/10), infrequent (> 1/1000 and < 1/10), infrequent (>< 1/100), rare (> 1/10 000 and < 1/100), rare (>< 1/1000), very rare (

Dermatological reactions:  infrequently-rash (erythematous, maculopapular, pustular), skin irritation, including pain, burning sensation, tingling sensation on the skin, itching, dry skin, contact dermatitis; rarely-eczema, periorbital edema, erythema.

Allergic reactions:  rarely – urticaria, angioedema, eczema.

From the side of the visual organ:  rarely-conjunctival irritation.

The patient should inform the doctor if any of the above-mentioned side effects occur.

How to take, course of use and dosage

The cream is applied externally.

In adults and children from birth to 18 years of age, the cream is applied to the affected areas of the skin in a thin layer 3-4 times a day.

When using gauze bandages, the frequency of application can be reduced to 1-2 times/day.

The duration of treatment depends on the form and severity of the disease and averages 7-14 days.

Special instructions

Do not apply Fucidin to the skin around the eyes, as fusidic acid, if it gets into the eyes, causes conjunctival irritation.

Fucidin cream contains butylhydroxyanisole, cetyl alcohol and potassium sorbate, which can cause local allergic skin reactions (for example, contact dermatitis). Butylhydroxyanisole can also cause eye and mucosal irritation.

When fusidic acid is used, bacterial resistance may develop. As with other antibiotics, prolonged or repeated use may increase the risk of developing antibiotic resistance.

Influence on the ability to drive vehicles and work with mechanisms. The effect on the ability to drive vehicles and complex mechanisms was not revealed.

Form of production

Cream for external use 2% homogeneous, from white to almost white in color.

Storage conditions

At a temperature not exceeding 25 °C.

Shelf

life is 3 years.

Active ingredient

Fusidic acid

Conditions of release from pharmacies

By prescription

Dosage form

cream

Description

For children as prescribed by a doctor, For adults as prescribed by a doctor, For children from birth

Indications

Skin Infections