Heparin-Acrichin 1000gel for external use 1 thousandIU/g, 50g

Composition

>of 100 g of gel contains:  active substance: sodium heparin in terms of dry matter-0.83 g (100000 ME); excipients: methyl parahydroxybenzoate-0.15 g, carbomer 940-1.25 g, trometamol-0.85 g, ethanol 96% (rectified ethyl alcohol) – 24 g, lavender oil-0.02 g, orange blossom oil (neroli oil) – 0.01 g, purified water – up to 100 g.

Pharmacological action

ATX code: C 05 VA 03 Pharmacological Properties Pharmacodynamics direct anticoagulant, has anti-inflammatory, antiproliferative, decongestant and analgesic effects. Reduces platelet aggregation, binds to antithrombin III, preventing the transition of prothrombin to thrombin. Inhibits the activity of thrombin. Reduces the activity of hyaluronidase, increases the fibrinolytic properties of blood. Improves microcirculation and activates tissue metabolism, thereby accelerating the resorption of hematomas and blood clots, ultimately restoring the patency of the veins, clinically this is accompanied by a pronounced analgesic and anti-inflammatory effect. Pharmacokinetic Sansignificant amounts of heparin are absorbed from the skin surface into the systemic circulation. The maximum concentration of the Active ingredient in the blood is noted 8 hours after application. Elimination of heparin mainly occurs through the kidneys, with a half-life of 12 hours.

Indications

-Thrombophlebitis of superficial veins; – localized infiltrates and edema of soft tissues;- injuries of tendons and joints; – bruises of soft tissues and joints.

Contraindications

-Hypersensitivity to any of the components of the drug, – ulcerative-necrotic skin changes in the places of the intended application of the gel, – traumatic violation of the integrity of the skin, – reduced blood clotting, – thrombocytopenia.

Side effects

– Allergic skin reactions, – hyperemia of the skin.

Interaction

It is not recommended to mix with other products for external use. Do not prescribe topically simultaneously with nonsteroidal anti-inflammatory drugs, tetracyclines, antihistamines. Concomitant use of the gel with oral anticoagulants may cause prolongation of prothrombin time.

How to take, course of use and dosage

Externally. The gel is applied in a thin layer on the affected area at the rate of 3-5 cm of gel on a skin area with a diameter of 3-5 cm and gently rubbed into the skin. Apply 1-3 times a day daily until the disappearance of inflammatory phenomena, on average from 3 to 7 days. The duration of treatment is determined by the doctor.

Overdose

Overdose is unlikely due to the low absorption of the gel components. It is manifested by bleeding. Protamine sulfate (a chemical antagonist) is removed.

Special instructions

It is not recommended to use for bleeding, as well as on open wounds, mucous membranes and in the presence of local purulent processes. Use with extreme caution in case of increased vascular permeability. The use of the gel is not recommended for deep venous thrombosis.

Form of production

Gel for external use.

Storage conditions

At a temperature of 15 to 25 °C. Keep out of reach of children.

Shelf

life is 2 years.

Active ingredient

Sodium Heparin

Dosage form

gel for external use

Description

Nursing mothers as prescribed by a doctor, For adults, For pregnant women

Indications

Tendon inflammation, Varicose veins, Thrombophlebitis, Swelling after injuries and operations, Bruises, Bruises, Dislocations and sprains