Hymecromone-SZ pills 200mg, 20pcs

Composition

Per tablet: Active ingredient:

Hymecromone – 200 mg;

excipients:

potato starch-45.0 mg,

gelatin -3.0 mg,

sodium lauryl sulfate-1.0 mg,

magnesium stearate-1.0 mg

Pharmacological action

Pharmacotherapy group: choleretic agent. ATX code: A 05 AX 02 Pharmacological properties Pharmacodynamics heluretic preparation. Increases the formation and excretion of bile. It has a selective antispasmodic effect on the bile ducts and sphincter of Oddi (does not reduce peristalsis of the gastrointestinal tract (GIT) and blood pressure (BP)). Reduces stagnation of bile, prevents the crystallization of cholesterol and thereby the development of cholelithiasis.

Pharmacokinetics

When taken orally, it is easily absorbed from the digestive tract, weakly binds to plasma proteins. The maximum concentration in the blood serum is reached in 2-3 hours. The elimination half-life is about 1 hour. Hymecromone is excreted by the kidneys (about 93% in the form of glucuronate,1.4% – sulfonate,0.3% – unchanged).

Indications

Dyskinesia of the biliary tract and sphincter of Oddi by hyperkinetic type, non-calculous chronic cholecystitis, cholangitis, cholelithiasis; condition after surgical interventions on the gallbladder and biliary tract. Decreased appetite, nausea, constipation, vomiting (due to bile hyposecretion).

Use during pregnancy and lactation

There are no data on the safety of using Hymecromone during pregnancy and lactation. The use of the drug Gimecromon-SZ during pregnancy and during breastfeeding is permissible according to the doctor’s prescription only in cases where the potential benefit to the mother exceeds the potential risk to the fetus and child.

Contraindications

Hypersensitivity. Biliary tract obstruction, renal / hepatic insufficiency, ulcerative colitis, Crohn’s disease, peptic ulcer of the stomach and duodenum, hemophilia. Children under 7 years of age.

Side effects

Possible allergic reactions: diarrhea, flatulence, abdominal pain, ulceration of the gastrointestinal mucosa, headache. If you experience any of the side effects listed in the instructions or if they get worse, or if you notice any other side effects not listed in the instructions, tell your doctor.

Interaction

Morphine weakens the effect of hymecromone. When co-administered with metoclopramide, the effect of both drugs is weakened, which increases the effects of indirect anticoagulants.

How to take, course of use and dosage

Inside,30 minutes before meals; adults-200-400 mg (1-2 tablets) three times a day. The daily dose is 1200 mg. Children from 7 years of age: 200 mg (1 tablet) once or three times a day. The daily dose is 600 mg. The course of treatment is 2 weeks. If you miss a dose, you should take the drug as soon as possible or, if the time for the next dose is approaching, do not take the missed dose. Do not take a double dose at once. If there is no improvement after treatment, or if the symptoms worsen or new symptoms appear, you should consult your doctor. Use the drug only according to the indications, the method of use and in the doses indicated in the instructions.

Overdose

So far, no overdose cases have been reported.

Special instructions

It does not impair the secretory function of the digestive glands and intestinal absorption processes.

Influence on the ability to drive vehicles and mechanisms

The drug Gimecromon-SZ does not affect the ability to drive vehicles and engage in other potentially dangerous activities that require increased concentration of attention and speed of psychomotor reactions.

Storage conditions

In a place protected from light, at a temperature not exceeding 25 °C. Keep out of reach of children.

Shelf

life is 3 years. Do not use after the expiration date.

Active ingredient

Gimecromon

Dosage form

Tablets