Ketonal cream 5%, 30g

Composition

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of 1 g of cream for external use contains:

Active ingredient:

ketoprofen – 50 mg;

Auxiliary substances:

methyl parahydroxybenzoate,

propyl parahydroxybenzoate,

propylene glycol,

isopropyl myristate,

petroleum jelly (white),

elfacos ST9,

propylene glycol glyceryl oleate,

magnesium sulfate,

water.

Pharmacological action

PHARMACOTHERAPY GROUP:  Nonsteroidal Anti-inflammatory drug (NSAID)

ATX Code: MO 2 AE 03

PHARMACOLOGICAL PROPERTIES

Ketoprofen is a non – steroidal anti-inflammatory drug, the main properties of which are analgesic, anti-inflammatory and decongestant effects.

It penetrates well into the subcutaneous tissue, ligaments and muscles, into the synovial fluid and reaches therapeutic concentrations there. The concentration of the drug in the plasma is extremely low. Ketoprofen does not have a negative effect on the condition of articular cartilage.

Indications

Symptomatic therapy of diseases and inflammatory processes of various origins, including: – Rheumatoid arthritis and periarthritis. – Ankylosing spondylitis (Ankylosing spondylitis). – Psoriatic arthritis. – Reactive arthritis (Reiter’s syndrome). – Osteoarthritis of various localization. – Tendinitis. – Bursitis. – Myalgia. – Neuralgia. – Sciatica. – Injuries of the musculoskeletal system (including sports), bruises of muscles and ligaments, sprains of ligaments, ruptures of ligaments and tendons of muscles.

Contraindications

-Hypersensitivity to ketoprofen, or other components of the drug, as well as salicylates or other nonsteroidal anti-inflammatory drugs. – An indication in the anamnesis of asthma attacks after the use of NSAIDs and salicylates. – The third trimester of pregnancy. – Children under 12 years of age. – Violation of the integrity of the skin: – Eczema. – Wet dermatitis. – An open or infected wound.

With caution: impaired liver and/or kidney function, erosive and ulcerative lesions of the gastrointestinal tract, blood diseases, bronchial asthma, chronic heart failure.

Interaction

Concomitant use of other topical forms (ointments, gels) containing ketoprofen or other NSAIDs is not recommended.

Simultaneous use of acetylsalicylic acid reduces the degree of binding of ketoprofen to plasma proteins.

Ketoprofen reduces the elimination of methotrexate and increases its toxicity.

Interactions with other drugs and the effect on their elimination are not significant.

How to take, course of use and dosage

For external use.

Apply a small amount of cream (3-5 cm) with light rubbing movements in a thin layer on the skin of the inflamed or painful area of the body 2-3 times a day.

The duration of treatment should not exceed 14 days.

Overdose

Symptoms: irritation, erythema, pruritus.

Treatment: Discontinue the medication and consult a doctor.

Conduct symptomatic therapy.

Special instructions

It is necessary to avoid getting the drug on the mucous membranes and in the eyes.

If you experience any side effects, you should stop using the drug and consult a doctor.

During therapy, direct sunlight and ultraviolet radiation should be avoided.

If you forget to apply the cream, apply it at the time when the next dose should be applied, but do not double it.

The cream can be used in combination with other forms of the drug were Ketonal: capsule ( was Ketonal caps. 50 mg pack. 25 Lek D. D. ), tablets ( was Ketonal table. p. about. 100 mg pack. 20 Lek D. D. ), candles ( I Ketonal supp. 100 mg pack. 12 Lek D. D. ). The total daily dose of whatever drug doses should not exceed 200 mg.

Form of production

White or almost white homogeneous cream.

Storage conditions

At a temperature not exceeding 25 °C

Shelf life

5 years

Active ingredient

Ketoprofen

Dosage form

cream