Ketoprofen gel for external use 2.5%, 50g – Cheminot

Composition

100 g of gel contains: Active ingredient: ketoprofen 2,5 Gspomogatelnye substances: carbopol 940, ethanol%% (ethanol), trollamine, nipagine (metiparahydroxybenzoate), water.

Pharmacological action

Pharmacotherapeutic grouppsteroidal anti-inflammatory drug (NSAID)ATX code: M02AA10 Pharmacological activitycondicates local anti-inflammatory, analgesic effects. The main mechanism of action of the drug is associated with the suppression of cyclooxygenase 1 and 2, which regulates prostaglandin synthesis. With joint syndrome, the use of the drug can reduce pain at rest and during movement, reduce morning stiffness, and swelling of the joints. Pharmacokinetics When applied topically, it is absorbed slowly, practically does not accumulate. The bioavailability of the gel is about 5%. After use at a dose of 50-150 mg, the plasma concentration after 5-8 hours is 0.08-0.15 mcg / ml. It is metabolized by conjugation with glucuronic acid. No active metabolites are formed.

Indications

• for diseases of the musculoskeletal system (joint syndrome in rheumatism and gout exacerbation, rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, osteoarthritis, osteochondrosis with radicular syndrome, sciatica, inflammatory damage to ligaments, tendons, bursitis, sciatica, lumbago);
• Muscle pain of rheumatic and non-rheumatic origin;
• Post-traumatic inflammation of the soft tissues and musculoskeletal system (injuries and ruptures of ligaments, bruises).

Contraindications

Hypersensitivity, wet dermatoses, eczema, infected abrasions, wounds, pregnancy, lactation, children (up to 12 years).

Side effects

Rarely-allergic reactions: hyperemia of the skin, photosensitization, skin exanthema, purpura. In such cases, treatment with the drug should be discontinued. Itching, burning sensation at the site of application of the drug.

Interaction

When ketoprofen is applied externally in the form of a gel, drug and other interactions have not been established.

How to take, course of use and dosage

Externally. A strip of gel 4-6 cm long is applied with light massaging movements to the skin in the area of soreness and inflammation. The duration of use without consulting a doctor is not more than 10 days.

Overdose

Extremely low systemic absorption of the active components of the drug with external use makes overdose almost impossible.

Special instructions

Do not apply to open wounds or inflamed skin! Avoid contact with eyes (risk of conjunctival irritation) and mucous membranes. After working with the gel, you should immediately wash your hands. Do not use with occlusal (airtight) dressings! There is no data on the effect on the ability to drive a car or work with equipment.

Form of production

Gel for external use 2.5%.

Storage conditions

Store in a dark, dry place at a temperature of 15-25 °C. Keep out of reach of children!

Shelf

life is 2 years.

Active ingredient

Ketoprofen

Dosage form

gel for external use