Loratadin-Teva pills 10mg, 10pcs

Composition

Tablets

Pharmacological action

Symptomatic treatment:

– seasonal and year-round allergic rhinitis;

– chronic idiopathic urticaria.

Indications

Symptomatic treatment:

– seasonal and year-round allergic rhinitis;

– chronic idiopathic urticaria.

Contraindications

-hypersensitivity to loratadine and other components of the drug;

– lactose intolerance, lactase deficiency, glucose-galactose malabsorption

— – pregnancy;

– breast-feeding period;

– children under 3 years of age.

With caution:  severe CRF (creatinine clearance less than 30 ml / min); severe hepatic insufficiency.

Side effects

the incidence of adverse reactions are classified according to the recommendations of the world health organization: very often – at least 10%; often – not less than 1% and less than 10%; infrequently – no more than 0.1% and less than 1%; rarely – not less than 0.01% and less than 0.1%; very rarely – less than 0.01%, including isolated cases.

Nervous system disorders: often-headache, nervousness; infrequently-insomnia, drowsiness; rarely-dizziness; in children-headache, increased nervous excitability, sedation.

From the digestive system: infrequently-increased appetite; rarely-nausea, gastritis, dry mouth, impaired liver function.

Allergic reactions: rarely – skin rash, anaphylaxis.

From the cardiovascular system: rarely-tachycardia, palpitation.

Skin and subcutaneous tissue disorders: rarely-alopecia.

Other services: infrequently – feeling tired.

Interaction

Loratadine does not potentiate the effects of alcohol.

Taking loratadine with a meal may slightly delay absorption (on average for 1 hour) without changing the clinical effect.

Erythromycin and cstoconazole (inhibitors of the CYP3A4 isoenzyme), cimetidine (inhibitor of the CYP3A4 and CYP2D6 isoenzymes) increase the Cmax of loratadine and its active metabolite in the blood. There are no clinically significant changes. Loratadine reduces the Cmax of erythromycin in plasma by 15%.

How to take, course of use and dosage

Inside, before eating.

Adults and children over 12 years of age and weighing more than 30 kg: 10 mg 1 time a day. Children from 3 to 12 years of age with a body weight of more than 30 kg-10 mg 1 time a day; with a body weight of less than 30 kg-5 mg 1 time a day.

The duration of treatment depends on the duration of symptoms of the disease. If the patient’s condition does not improve within 3 days after starting treatment, then loratadine is not effective.

Patients with severe CRF (creatinine clearance less than 30 ml / min) and severe hepatic insufficiency:  5 mg 1 time a day daily or 10 mg 1 time a day every other day. Elderly patients-no dose adjustment is required.

Overdose

Symptoms: headache, drowsiness, tachycardia. Extrapyramidal disorders and palpitations were observed in children weighing less than 30 kg when ingested at a dose of more than 10 mg.

Treatment: gastric lavage, taking activated charcoal; symptomatic and supportive therapy. For children,0.9% sodium chloride solution is used for washing, for adults, water can be used for washing.

Saline laxative solutions and enterosorbents are indicated for rapid elimination of loratadine from the gastrointestinal tract. Loratadine is not eliminated by hemodialysis or peritoneal dialysis.

Special instructions

Loratadine should be taken with caution in patients with severe hepatic insufficiency, as loratadine clearance may be reduced in such patients. The safety and efficacy of loratadine in children under 3 years of age is unknown, so the drug is contraindicated for use in this age group.

Treatment with loratadine should be discontinued at least 48 hours prior to skin allergy testing, as antihistamines may hide or reduce positive skin reactions. Loratadine can cause dry mouth in some patients, so people at risk should have oral hygiene because of the risk of tooth decay. Children under 12 years of age with a body weight of less than 30 kg should use loratadine in lower doses.

Influence on the ability to drive motor vehicles and manage mechanisms

When using loratadine, caution should be exercised when driving vehicles and operating complex mechanisms, given that during use, side effects such as drowsiness and dizziness may develop, affecting the ability to concentrate and psychomotor reactions.

In case of kidney failure

With caution: CRF (creatinine clearance less than 30 ml / min).

With impaired liver function

Loratadine should be taken with caution in patients with severe hepatic insufficiency, as loratadine clearance may be reduced in such patients.

Active ingredient

Loratadine

Dosage form

Tablets

Description

Children over 3 years old, For adults

Indications

Diathesis, Dermatosis, Dermatitis, Runny Nose, Allergic Runny Nose, Urticaria, Pollinosis, Allergy, Conjunctivitis, Allergic Conjunctivitis