Maxicold Lore, spray, 40ml

Composition

Composition per 100 ml:

Active ingredient:  

• hexetidine – in terms of 100% substance) – 200 mg (0.2%).

Auxiliary substances:

• sodium shrinathaji – 40 mg,
• citric acid monohydrate – 70 mg,
• sodium hydroxide (sodium hydroxide) – 19 mg,
• glycerol (glycerin) – 17000 mg,
• ethanol (ethyl alcohol) – 4000 mg,
• lauromacrogol (macrogalleria ether) – 1500 mg,
• cineol (the evkaliptola) – 20 mg,
• levomenthol (L-Menthol) – 20 mg
• peppermint leaf oil is 10 mg,
• purified water – up to 100,0 ml.

Pharmacological properties

Pharmacotherapeutic group: antiseptic

ATX code: A 01AB 12

Pharmacological properties

Pharmacodynamics

Antiseptic agent for topical application on the mucous membranes. It has antimicrobial, antifungal, analgesic, enveloping and deodorizing effects. Antimicrobial action of Maxicold® Ent is associated with suppression of oxidative reactions of bacterial metabolism (hexetidine is a thiamine antagonist).

The drug has a wide spectrum of antibacterial and antifungal effects, in particular against gram-positive bacteria and fungi of the genus Candida, but the drug Maxicold® Ent can also have an effect in the treatment of infections caused, for example, by Pseudomonas Aeruginosa or Proteus. At a concentration of 100 mg / ml, the drug suppresses most bacterial strains. No stability development was observed.

Maxicold® Ent has a weak anesthetic effect on the mucous membrane.

The drug has an antiviral effect against influenza A viruses, respiratory syncytial virus (MS-virus), herpes simplex virus type 1, affecting the respiratory tract.

Pharmacokinetics

After a single application, the local action of hexetidine lasts 10-12 hours. The drug is practically not absorbed from the surface of the mucous membranes and does not have a systemic effect. After a single application of the Active ingredient, its traces are found on the gum mucosa for 65 hours. In dental plaques, active concentrations persist for 10-14 hours after application.

Indications

Infectious and inflammatory diseases of the oral cavity and pharynx (tonsillitis, including Plaut-Vincent’s sore throat, pharyngitis, stomatitis, aphthous ulcers of the oral cavity, glossitis, periodontitis, gingivitis, periodontal disease, periodontal diseases, alveolitis), bleeding gums. In acute respiratory infections – as an auxiliary agent, as part of complex therapy.

Fungal infections of the oral cavity, pharynx and larynx (thrush).

Injuries and surgical interventions in the oral cavity, pharynx and larynx (both before and after their implementation), including prevention of infection of the alveoli after tooth extraction.

As an oral hygiene product to eliminate unpleasant odors (deodorizing effect).

Prevention of superinfections in collapsing tumors of the oral cavity and larynx.

Use during pregnancy and lactation

There is no information about any adverse effects of hexetidine during pregnancy and breast-feeding. Before prescribing the drug to pregnant or lactating women, the doctor should carefully weigh the benefits of treatment for the mother and the possible risk to the fetus and child, given the lack of sufficient data on the penetration of the drug through the placenta and into breast milk.

Contraindications

Hypersensitivity, atrophic pharyngitis, children under 3 years of age.

Side effects

Allergic reactions; burning of the oral mucosa; if accidentally swallowed-nausea; with prolonged use, a violation of taste sensations may occur.

If any of the side effects listed in the instructions get worse, or you notice other adverse reactions that are not listed in the instructions, tell your doctor.

Interaction

Currently, there is no information on interactions with other medicinal products.

How to take, course of use and dosage

Topically, after a meal, or in between meals. With the help of a spray, the affected areas in the oral cavity and pharynx are treated. To use the drug correctly, follow these steps: :

• Remove the cap from the cylinder and install the spray gun in the appropriate opening in the upper part of the cylinder.
• During the first use, it is necessary to first perform several short-term taps on the spray gun (in order to ensure uniform spraying of the contents of the cylinder).
• Inject the required amount of the drug into the oral cavity by pressing the nebulizer all the way down 3-4 times. During the use of the drug, you should hold your breath.
• After use, remove the spray gun, rinse it in running water and dry it at room temperature out of the reach of children.
• Keep the nebulizer in the package along with the drug. Adults and children over 3 years of age: frequency of use-2-3 times a day. If necessary, more frequent use of the drug is possible. The course of treatment is 5-7 days.

Overdose

Hexetidine in the indicated dosage is non-toxic. Ingestion of large amounts of the drug leads to vomiting, so significant absorption is not expected.

No cases of ethanol poisoning from overdose have been described. Acute alcohol poisoning is very unlikely, but theoretically possible if a large dose of the drug is swallowed by a small child. In any case of overdose, consult your doctor immediately.

Treatment is symptomatic: intake of enterosorbents (activated charcoal), gastric lavage, heavy drinking. Gastric lavage is required within 2 hours after ingestion of an excessive dose.

Special instructions

Children can use the drug from an age when they do not resist a foreign object (nebulizer) in their mouth when applying the spray and are able to hold their breath when injecting the drug.

The spray should not be inhaled; avoid contact with the eyes. After applying the spray, the applicator should be rinsed with warm water.

It should be borne in mind that the spray contains ethanol – 24-48 mg in a daily dose.

In the absence of a general reaction to taking the drug, performing potentially dangerous activities that require special attention and rapid reactions (including driving a car) is not contraindicated.

Attention! The cylinder is under pressure. Do not burn, pierce or open, even if the cylinder is empty.

Influence on the ability to drive vehicles and mechanisms

The drug does not have a negative effect on driving vehicles and performing potentially dangerous activities that require increased concentration of attention and speed of psychomotor reactions.

Product form

spray for topical application

Storage conditions

At a temperature not exceeding 25 ° C. Keep out of reach of children.

Do not freeze!

Shelf life

2 years

Active ingredient

Hexatidine

Dosage form

oral spray

Description

Children over 3 years of age, For adults, Pregnant women as prescribed by a doctor, Nursing mothers as prescribed by a doctor

Indications

Stomatitis, Sore Throat, Gum Disease, Pharyngitis, Oral Inflammation, Periodontitis, Tonsillitis, Flu, Periodontitis, Thrush