Maxicold Rhino, sachets, orange flavour, 10pcs

Composition

Active ingredients:  

phenylephrine hydrochloride-10 mg,

phenyramine maleate-20 mg,

ascorbic acid-50 mg,

paracetamol-325 mg.

Auxiliary substances:

Powder for preparation of oral solution [orange]:

citric acid (citric acid anhydrous) – 750,00 mg, malic acid to 7.50 mg, sucrose (sugar) – 13599,17 mg, titanium dioxide – 2,20 mg, sodium citrate (sodium citrate anhydrous) – of 123.00 mg, orange flavor – 52,50 mg, quinoline yellow dye – 0.33 mg, calcium phosphate (tricalcium phosphate) to 60.00 mg, ethyl cellulose and 0.30 mg.

Pharmacological properties

Pharmacotherapeutic group: remedy to eliminate the symptoms of cold and “cold” (non-narcotic analgesic tool + alpha-agonists + H₁-histamine receptor blocker + vitamin).

ATX code: N02BE51

Pharmacological properties

Combined drug, has antipyretic, vasoconstrictor, analgesic and anti-allergic effects. Paracetamol has an antipyretic and analgesic effect: it reduces the pain syndrome observed in “cold” diseases – sore throat, headache, muscle and joint pain, reduces high fever. Phenyramine has an anti-allergic effect: it eliminates swelling and hyperemia of the mucous membranes of the nasal cavity, nasopharynx and paranasal sinuses, reduces runny nose and lacrimation. Phenylephrine has a vasoconstrictive effect: it reduces the swelling of the nasopharyngeal mucosa. Ascorbic acid (vitamin C) makes up for the increased need for vitamin C in “colds” and flu, especially in the initial stages of the disease; increases the body’s resistance to infectious diseases. The combined action of phenyramine and phenylephrine reduces nasal congestion and significantly facilitates nasal breathing.

Indications

Symptomatic treatment of acute respiratory viral infections, “colds”, flu, which are accompanied by:

• high fever,
• chills,
• headache,
• runny nose,
• sinus and throat pain,
• nasal congestion,
• sneezing,
• muscle and joint pain.

Use during pregnancy and lactation

The use of the drug during pregnancy is contraindicated.

If it is necessary to use the drug during breastfeeding, breastfeeding should be discontinued.

Contraindications

• Hypersensitivity to individual components of the drug.
• Severe renal / hepatic insufficiency.
• Pregnancy.
• Breast-feeding period.
• Children’s age (up to 12 years).

Use caution when using:

• Arterial hypertension.
• Diabetes mellitus.
• Angle-closure glaucoma.
• Diseases of the liver or kidneys.
• Prostatic hyperplasia.
• Lack of glucose-6-phosphate dehydrogenase.

Side effects

Possible allergic reactions, drowsiness, nausea, epigastric pain, dry mouth, paresis of accommodation, increased excitability, dizziness, increased blood pressure, sleep disturbance, urinary retention, rarely: anemia.

Interaction

It is recommended to refrain from taking the drug when taking monoamine oxidase inhibitors. The risk of hepatotoxic effects of paracetamol increases with simultaneous use of barbiturates, diphenine, carbamazepine, rifampicin, zidovudine and other inducers of microsomal liver enzymes.

Antidepressants, antiparkinsonian and antipsychotic medications, and phenothiazine derivatives increase the risk of urinary retention, dry mouth, and constipation.

Reduces the hypotensive effect of guanethidine, which in turn increases the alpha-adrenostimulating activity of phenylephrine.

How to take, course of use and dosage

Dissolve the contents of one packet in 1 cup of boiled hot water. Use it hot. You can add sugar to taste.

A second dose can be taken every 4 hours (maximum 3 doses within 24 hours).

Maxicold Reno for flu and colds can be used at any time of the day, but the best effect comes from taking the drug before going to bed, at night.

If there is no relief of symptoms within 3 days after starting the drug, you should consult a doctor.

Overdose

Symptoms of the drug: hepatotoxic and nephrotoxic effects nausea, vomiting, epigastric pain; in severe cases, liver failure, encephalopathy and coma develop.

Treatment: you should do a gastric lavage, take activated charcoal and consult a doctor.

Special instructions

In order to avoid toxic liver damage, paracetamol should not be combined with the intake of alcoholic beverages, as well as taken by people who are prone to chronic alcohol consumption.

The risk of developing liver damage increases in patients with alcoholic hepatosis.

In the case of taking the drug for patients suffering from diabetes or who are on a low-sugar diet, it should be borne in mind that each package contains 13,599.17 mg of sugar, which corresponds to 1 XE.

Do not use the drug from damaged packages.

Influence on the ability to drive vehicles and mechanisms

During the period of use of the drug, it is not recommended to drive vehicles and various mechanisms, as well as carry out other potentially dangerous activities that require increased attention and speed of mental and motor reactions.

Form of production

Maxicold Reno. Powder for preparation of an oral solution

Storage conditions

Store at a temperature not exceeding 30 °C.

Shelf life

2 years

Active ingredient

Paracetamol, Phenylephrine, Phenyramine, Ascorbic acid

Dosage form

solution for oral use

Description

For adults, Children over 12 years of age

Indications

Cold, Flu, Runny Nose